Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

7 questions · 7 findings · 5 reviews · Dementia and Cognitive Improvement

No studies found 1 · 14.3%GRADE not reported 2 · 28.6%Very low 0 · 0%Low 1 · 14.3%Moderate 2 · 28.6%High 1 · 14.3%

Souvenaid vs placebo

Any adverse events · Apathy in people with mild‐to‐moderate Alzheimer's disease

Souvenaid showed no clear difference in any adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Rivastigmine vs placebo

Risk for at least one adverse event per patient · Apathy in people with mild‐to‐moderate Alzheimer's disease

Rivastigmine probably leads to higher incidence of adverse events (at least one adverse event by 26 weeks) compared with placebo (moderate certainty).

1 finding from 1 review

Omega‐3 vs placebo

Serious adverse events "Defined as events that result in death, hospitalization, prolongation of hospitalization, or are life threatening (based on the judgment of the study physician)" (Quinn 2010) · Apathy in people with mild‐to‐moderate Alzheimer's disease

Omega‐3 PUFA supplements showed no clear difference in serious adverse events "Defined as events that result in death,… compared with placebo (high certainty).

1 finding from 1 review