What do systematic reviews say?

Primary surgical intervention (curettage, peripheral osteotomy, or resection) vs Primary non-surgical intervention (intralesional corticosteroids, subcutaneous calcitonin, interferon alpha, or imatinib)

The review found no eligible studies for this question.

• Interventions for central giant cell granuloma (CGCG) of the jaws 2009 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Any experimental intervention (surgical or non-surgical) vs None (placebo or no treatment)

The review found no eligible studies for this question.

• Interventions for treating bisphosphonate‐related osteonecrosis of the jaw (BRONJ) 2016 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Any surgical or non-surgical technique or material used for the treatment of post-extraction bleeding vs Placebo, no treatment, or another active antifungal intervention

The review found no eligible studies for this question.

• Interventions for treating post‐extraction bleeding 2018 · Cochrane All outcomes
  No data are available as no RCTs have been conducted on interventions to treat post-extraction bleeding
  0 studies
  No studies found

Combined paracetamol plus ibuprofen in a single tablet (e.g. paracetamol 1000 mg/ibuprofen 400 mg or 500/200 mg) vs Single drugs given separately (paracetamol 1000 mg or ibuprofen 400 mg)

• Ibuprofen and/or paracetamol (acetaminophen) for pain relief after surgical removal of lower wisdom teeth 2013 · Cochrane All outcomes

  Study period (immediate postoperative)
  The majority of adverse events were minor in nature and usually included nausea, vomiting, headaches and dizziness. Side effect profiles have not been included in a meta-analysis as multiple adverse events were…
  2 studies
  GRADE not reported

Ibuprofen (single postoperative oral dose; 200 mg to 512 mg) vs paracetamol

• Ibuprofen and/or paracetamol (acetaminophen) for pain relief after surgical removal of lower wisdom teeth 2013 · Cochrane All outcomes

  Study period (immediate postoperative)
  The majority of adverse events were minor in nature and usually included nausea, vomiting, headaches and dizziness. Side effect profiles have not been included in a meta-analysis as multiple adverse events were…
  7 studies
  GRADE not reported

Oral paracetamol vs placebo

Paracetamol (single oral dose, any dose or formulation; subgroups up… showed no clear difference in patients with one or more adverse events compared with placebo; GRADE not reported.

• Paracetamol for pain relief after surgical removal of lower wisdom teeth 2007 · Cochrane All outcomes

  up to 7 days
  RR 1.19 [0.90, 1.57]
  17 studies · 1645 participants
  GRADE not reported