Prednisone plus azathioprine vs prednisone
Adverse events · bullous pemphigoid
1 finding from 1 review
- no estimate extractedStudies not reportedVery low
Findings
What do systematic reviews say?
11 questions · 11 findings · 4 reviews · Skin
No studies found 1 · 9.1%GRADE not reported 0 · 0%Very low 3 · 27.3%Low 2 · 18.2%Moderate 5 · 45.5%High 0 · 0%
Methylprednisolone plus azathioprine vs methylprednisolone plus dapsone
Adverse events at 1 year · bullous pemphigoid
1 finding from 1 review
- no estimate extractedStudies not reportedVery low
Corticosteroid creams/ointments: mometasone furoate cream 3 times/week vs 2 times/week
Primary outcome 3: Adverse events · people (all patch‐tested) with hand eczema > 6 months that had cleared upon daily treatment for a maximum of 9 weeks with mometasone…
Corticosteroid creams/ointments: mometasone furoate cream 3 times/week showed no clear difference in primary: adverse events compared with 2 times/week (low certainty).
1 finding from 1 review
- RR 1.76 [0.45, 6.83]1 study · 72 participantsLow
Oral dehydroepiandrosterone vs placebo
Minor adverse events · patients with cutaneous disease in systemic lupus erythematosus
Oral dehydroepiandrosterone probably leads to higher adverse events: minor compared with placebo (moderate certainty).
1 finding from 1 review
- Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes onlyRR 10.5 [3.26, 33.75]1 study · 381 participantsModerate
Oral dehydroepiandrosterone vs placebo
Adverse events: severe · patients with cutaneous disease in systemic lupus erythematosus
Oral dehydroepiandrosterone showed no clear difference in adverse events: severe compared with placebo (moderate certainty).
1 finding from 1 review
- Interventions for cutaneous disease in systemic lupus erythematosus 2021 · Cochrane Headline outcomes onlyRR 0.09 [0.01, 1.66]1 study · 381 participantsModerate
Tacrolimus 0.1% vs mometasone furoate ointment
Primary outcome 3: Adverse events · people with moderate to severe chronic relapsing dyshidrotic eczema on hands
1 finding from 1 review
- no estimate extracted1 study · 16 participantsModerate
Nicotinamide plus tetracycline vs prednisone
Adverse events at 1 year · bullous pemphigoid
1 finding from 1 review
- no estimate extractedStudies not reportedVery low
Zinc tape vs povidone‐iodine
Adverse events associated with treatment · ulceration and other skin changes caused by nerve damage in leprosy
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Clobetasol propionate cream vs prednisone
Adverse events: severe complications at day 21 · bullous pemphigoid
Clobetasol propionate cream may leads to lower adverse events: severe complications at day 21 compared with oral prednisone (low certainty).
1 finding from 1 review
- RR 0.65 [0.5, 0.86]1 study · 341 participantsLow
Oral immunosuppressants: oral cyclosporin vs topical betamethasone dipropionate
Number of participants with any adverse event (primary tolerability outcome) · people with hand eczema, continuously for 6 months, significant disability, inadequate response to conventional treatment, confirmation by…
Oral immunosuppressants: oral cyclosporin showed no clear difference in primary: adverse events ‐ at least 1 adverse event compared with topical betamethasone dipropionate (moderate certainty).
1 finding from 1 review
- RR 1.22 [0.8, 1.86]1 study · 55 participantsModerate
Doxycycline vs prednisolone
Number of participants with grade 3‐4 (severe or life‐threatening) treatment‐related adverse events at 1 year (raw data) · bullous pemphigoid
Doxycycline probably leads to lower number of participants with grade 3‐4 (severe or life‐threatening)… compared with prednisolone (moderate certainty).
1 finding from 1 review
- RR 0.59 [0.35, 0.99]1 study · 234 participantsModerate