Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

133 questions · 133 findings · 44 reviews · Headline outcomes only

No studies found 19 · 14.3%GRADE not reported 4 · 3%Very low 40 · 30.1%Low 39 · 29.3%Moderate 23 · 17.3%High 8 · 6%

Moderate‐potency vs mild‐potency topical corticosteroid

Local adverse events: skin thinning; end of treatment (2‐5 weeks) · children and adults with mild to severe eczema

Moderate‐potency may leads to lower local adverse events: skin thinning; end of treatment (2‐5 weeks) compared with mild‐potency topical corticosteroid (low certainty).

1 finding from 1 review

Moderate‐potency vs mild‐potency topical corticosteroid

Systemic adverse events: abnormal cortisol; end of treatment (1‐6 weeks) · children and adults with mild to severe eczema

It is very uncertain whether moderate‐potency changes systemic adverse events: abnormal cortisol; end of treatment (6‐28… compared with mild‐potency topical corticosteroid (very low certainty).

1 finding from 1 review

Surgery plus whole brain radiotherapy (WBRT) vs stereotactic radiosurgery

Adverse events (moderate) · people with single or solitary brain metastasis

It is very uncertain whether surgery plus whole brain radiotherapy (WBRT) changes adverse events (moderate) compared with stereotactic radiosurgery (very low certainty).

1 finding from 1 review

Surgery plus whole brain radiotherapy (WBRT) vs stereotactic radiosurgery plus WBRT

Adverse events (moderate) · people with single or solitary brain metastasis

It is very uncertain whether surgery plus whole brain radiotherapy (WBRT) changes adverse events (moderate) compared with stereotactic radiosurgery plus WBRT (very low certainty).

1 finding from 1 review

Trapeziectomy with interpositional arthroplasty (T and IA) vs Artelon joint resurfacing

Adverse events Mild to moderate swelling · Patients with thumb (trapeziometacarpal joint) osteoarthritis

It is very uncertain whether trapeziectomy with interpositional arthroplasty (T and IA) changes adverse events Mild to moderate swelling compared with artelon joint resurfacing (very low certainty).

1 finding from 1 review

Summary of findings: Inhaled antibiotics plus IV antibiotics vs IV antibiotics

Adverse events (moderate) · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

It is very uncertain whether summary of findings: Inhaled antibiotics plus IV antibiotics changes adverse events moderate adverse events experienced during and after… compared with IV antibiotics only (very low certainty).

1 finding from 1 review

Aspirin plus antipsychotics vs placebo/no adjunctive treatment + antipsychotics

Adverse events: gastrointestinal – dyspeptic symptoms – self‐assessed as at least 'moderate' · patients with schizophrenia

It is very uncertain whether aspirin plus antipsychotics changes adverse events: gastrointestinal – dyspeptic symptoms –… compared with placebo plus antipsychotics (very low certainty).

1 finding from 1 review