Findings

What do systematic reviews say?

9 questions · 9 findings · 5 reviews · Headline outcomes only

No studies found 0 · 0%GRADE not reported 1 · 11.1%Very low 3 · 33.3%Low 3 · 33.3%Moderate 2 · 22.2%High 0 · 0%

Adverse events · antipsychotic‐related constipation

1 finding from 1 review

Pharmacological treatment for antipsychotic‐related constipation 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 240 participants
GRADE not reported

Adverse events relating to treatment Scale: mild, moderate, severe and total · children and young adults with CF

1 finding from 1 review

Inhaled mannitol for cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 22 participants
Low

Adverse events · people with bronchiectasis

Inhaled mannitol showed no clear difference in adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Inhaled hyperosmolar agents for bronchiectasis 2014 · Cochrane Headline outcomes only
OR 0.96 [0.61, 1.51]
2 studies · 804 participants
Moderate

Adverse events relating to treatment Scale: mild, moderate, severe and total · adults, children and young people with CF

1 finding from 1 review

Inhaled mannitol for cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
123 participants
Low

Adverse events relating to treatment Scale: mild, moderate, severe and total · adults, children and young people with CF

1 finding from 1 review

Inhaled mannitol for cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 600 participants
Moderate

Adverse events relating to treatment Scale: mild, moderate, severe and total · children and young adults with CF

1 finding from 1 review

Inhaled mannitol for cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
231 participants
Very low

Adverse events relating to treatment Scale: mild, moderate, severe and total · children and young adults with CF

1 finding from 1 review

Inhaled mannitol for cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
231 participants
Very low

Adverse events · adults and children with cystic fibrosis

1 finding from 1 review

Nebulised hypertonic saline for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 12 participants
Very low

Adverse events · Children aged 6‐60 months with cerebral malaria

1 finding from 1 review

Mannitol and other osmotic diuretics as adjuncts for treating cerebral malaria 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 156 participants
Low