What do systematic reviews say?

Low‐level laser therapy vs Placebo (sham) laser therapy

The review found no eligible studies for this question.

• Interventions for iatrogenic inferior alveolar and lingual nerve injury 2014 · Cochrane All outcomes
  SoF row 'Adverse events': This outcome was not reported in the included studies.
  0 studies
  No studies found

Combined paracetamol plus ibuprofen in a single tablet (e.g. paracetamol 1000 mg/ibuprofen 400 mg or 500/200 mg) vs Single drugs given separately (paracetamol 1000 mg or ibuprofen 400 mg)

• Ibuprofen and/or paracetamol (acetaminophen) for pain relief after surgical removal of lower wisdom teeth 2013 · Cochrane All outcomes

  Study period (immediate postoperative)
  The majority of adverse events were minor in nature and usually included nausea, vomiting, headaches and dizziness. Side effect profiles have not been included in a meta-analysis as multiple adverse events were…
  2 studies
  GRADE not reported

Ibuprofen (single postoperative oral dose; 200 mg to 512 mg) vs paracetamol

• Ibuprofen and/or paracetamol (acetaminophen) for pain relief after surgical removal of lower wisdom teeth 2013 · Cochrane All outcomes

  Study period (immediate postoperative)
  The majority of adverse events were minor in nature and usually included nausea, vomiting, headaches and dizziness. Side effect profiles have not been included in a meta-analysis as multiple adverse events were…
  7 studies
  GRADE not reported

Oral paracetamol vs placebo

Paracetamol (single oral dose, any dose or formulation; subgroups up… showed no clear difference in patients with one or more adverse events compared with placebo; GRADE not reported.

• Paracetamol for pain relief after surgical removal of lower wisdom teeth 2007 · Cochrane All outcomes

  up to 7 days
  RR 1.19 [0.90, 1.57]
  17 studies · 1645 participants
  GRADE not reported

Perioperative infraorbital nerve block vs Intravenous analgesia

• Infraorbital nerve block for postoperative pain following cleft lip repair in children 2016 · Cochrane All outcomes
  2 out of 3 studies reported this outcome. Both studies reported no difference between groups (Rajamani 2007 and Simion 2008: no adverse events attributable to either technique; Delgado 2005 did not report).
  2 studies
  GRADE not reported

Perioperative infraorbital nerve block vs Placebo (sham/placebo device)

• Infraorbital nerve block for postoperative pain following cleft lip repair in children 2016 · Cochrane All outcomes
  2 out of 3 studies reported this outcome. One study reported no differences between groups, and the other study reported more vomiting in the placebo group (Takmaz 2009: vomiting 40% placebo versus 10% intervention; P…
  2 studies
  GRADE not reported

Perioperative infraorbital nerve block vs Infiltration of the incision (peri-incisional infiltration)

• Infraorbital nerve block for postoperative pain following cleft lip repair in children 2016 · Cochrane All outcomes
  Of the 2 included studies, one study reported no difference between groups (Gaonkar 2004: no adverse events attributable to either technique), and the other study did not report this outcome.
  1 study
  GRADE not reported