Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

88 questions · 88 findings · 12 reviews · Kidney and Transplant

No studies found 12 · 13.6%GRADE not reported 0 · 0%Very low 34 · 38.6%Low 33 · 37.5%Moderate 9 · 10.2%High 0 · 0%

Surgical thrombectomy vs different types of endovascular interventions

Major adverse events · thrombosed haemodialysis arteriovenous fistulas and grafts

It is very uncertain whether surgical thrombectomy changes major adverse events compared with different types of endovascular interventions (very low certainty).

1 finding from 1 review

Surgical thrombectomy vs different types of endovascular interventions

Minor adverse events · thrombosed haemodialysis arteriovenous fistulas and grafts

It is very uncertain whether surgical thrombectomy changes minor adverse events compared with different types of endovascular interventions (very low certainty).

1 finding from 1 review

Azathioprine vs cyclophosphamide

Serious adverse events · adults with renal vasculitis for maintenance therapy

Azathioprine showed no clear difference in serious adverse events compared with cyclophosphamide (moderate certainty).

1 finding from 1 review

Leflunomide vs methotrexate

Serious adverse events* · adults with renal vasculitis for maintenance therapy

Leflunomide showed no clear difference in serious adverse events* compared with methotrexate (low certainty).

1 finding from 1 review

Antibiotics vs placebo

Discontinuation of medication due to adverse events · adults with renal vasculitis for maintenance therapy

Antibiotics showed no clear difference in adverse events causing study drug discontinuation compared with placebo (low certainty).

1 finding from 1 review