Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

116 questions · 116 findings · 16 reviews · Skin

No studies found 20 · 17.2%GRADE not reported 5 · 4.3%Very low 34 · 29.3%Low 29 · 25%Moderate 27 · 23.3%High 1 · 0.9%

Loratadine 10 mg vs mizolastine 10 mg

Withdrawals due to adverse events · patients with chronic spontaneous urticaria

Loratadine 10 mg showed no clear difference in adverse events leading to withdrawal: intermediate‐term duration of… compared with mizolastine 10 mg (low certainty).

1 finding from 1 review

Loratadine 10 mg vs emedastine 2 mg

Withdrawals due to adverse events · patients with chronic spontaneous urticaria

Loratadine 10 mg showed no clear difference in adverse events leading to withdrawal: intermediate‐term duration of… compared with emedastine 2 mg (moderate certainty).

1 finding from 1 review

Hydroxyzine 25 mg vs placebo

Withdrawals due to adverse events · patients with chronic spontaneous urticaria

Hydroxyzine 25 mg showed no clear difference in adverse events leading to withdrawal: intermediate‐term duration of… compared with placebo (low certainty).

1 finding from 1 review

Tonsillectomy vs no intervention

Proportion of participants with adverse events and severe adverse events · people with chronic plaque psoriasis

It is very uncertain whether tonsillectomy changes proportion of participants with adverse events and severe adverse… compared with no intervention (very low certainty).

1 finding from 1 review

Chemical peeling vs combined chemical peeling plus any active intervention

Participant‐assessed adverse events (short‐term) N of participants with adverse events · people with acne scars

It is very uncertain whether chemical peeling changes participant‐assessed adverse events (short‐term) N of participants… compared with combined chemical peeling plus any active intervention (very low certainty).

1 finding from 1 review