Findings

What do systematic reviews say?

8 questions · 8 findings · 3 reviews

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No studies found 2 · 25%GRADE not reported 0 · 0%Very low 4 · 50%Low 1 · 12.5%Moderate 1 · 12.5%High 0 · 0%

Balanced crystalloid solutions vs Normal saline

Adverse events ‐ hypokalaemia · children with severe dehydration due to diarrhoea

Balanced crystalloid solutions probably leads to lower adverse events: hypokalaemia compared with 0.9% saline (moderate certainty).

1 finding from 1 review

Balanced crystalloid solutions versus 0.9% saline for treating acute diarrhoea and severe dehydration in children 2023 · Cochrane Headline outcomes only
RR 0.54 [0.31, 0.96]
Studies not reported
Moderate

Balanced crystalloid solutions vs Normal saline

Adverse events: hyponatraemia · children with severe dehydration due to diarrhoea

Balanced crystalloid solutions showed no clear difference in adverse events: hyponatraemia compared with 0.9% saline (low certainty).

1 finding from 1 review

Balanced crystalloid solutions versus 0.9% saline for treating acute diarrhoea and severe dehydration in children 2023 · Cochrane Headline outcomes only
RR 1.41 [0.96, 2.07]
Studies not reported
Low

Dextrans vs crystalloid

Adverse events

The review found no eligible studies for this question.

1 finding from 1 review

Colloids versus crystalloids for fluid resuscitation in critically ill people 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Gelatins vs crystalloid

Adverse events

1 finding from 1 review

Colloids versus crystalloids for fluid resuscitation in critically ill people 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Albumin and fresh frozen plasma vs crystalloid

Adverse events

1 finding from 1 review

Colloids versus crystalloids for fluid resuscitation in critically ill people 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Starches vs crystalloid

Adverse events

1 finding from 1 review

Colloids versus crystalloids for fluid resuscitation in critically ill people 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Prophylactic plasma transfusion before surgery/invasive procedures vs no prophylactic plasma transfusion before surgery/invasive procedures (colloid, crystalloid, placebo, or no treatment)

Serious adverse events measured by surgery or procedure‐related complications within 30 days ‐ not reported · patients undergoing non‐cardiac surgery/invasive procedures

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic plasma transfusion for patients without inherited bleeding disorders or anticoagulant use undergoing… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prophylactic plasma transfusion before surgery/invasive procedures vs no prophylactic plasma transfusion before surgery/invasive procedures (colloid, crystalloid, placebo, or no treatment)

Serious adverse events measured by plasma transfusion‐related complications within 24 hours № of participants: 21 (1 RCT) · patients undergoing non‐cardiac surgery/invasive procedures

1 finding from 1 review

Prophylactic plasma transfusion for patients without inherited bleeding disorders or anticoagulant use undergoing… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low