Cannabidiol vs placebo
Adverse events · people with active UC
Cannabidiol probably leads to higher adverse events compared with placebo (moderate certainty).
1 finding from 1 review
- RR 1.28 [1.05, 1.56]1 study · 60 participantsModerate
Findings
What do systematic reviews say?
10 questions · 10 findings · 4 reviews
No studies found 6 · 60%GRADE not reported 0 · 0%Very low 1 · 10%Low 1 · 10%Moderate 1 · 10%High 1 · 10%
Cannabidiol vs placebo
Serious adverse events · people with active UC
Cannabidiol showed no clear difference in serious adverse events compared with placebo (low certainty).
1 finding from 1 review
- RR 0.15 [0.01, 2.83]1 study · 60 participantsLow
Cannabis oil (15% cannabidiol and 4% THC) vs placebo oil
Adverse events · Patients with active Crohn's disease
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Cannabis oil (5% cannabidiol sublingual oil) vs placebo oil
Adverse events · Patients with active Crohn's disease
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Cannabis oil (15% cannabidiol and 4% THC) vs placebo oil
Serious adverse events · Patients with active Crohn's disease
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Cannabis oil (5% cannabidiol sublingual oil) vs placebo oil
Serious adverse events · Patients with active Crohn's disease
It is very uncertain whether cannabis oil (5% cannabidiol sublingual oil) changes serious adverse events compared with placebo oil (very low certainty).
1 finding from 1 review
- RR 0.9 [0.07, 12.38]1 study · 19 participantsVery low
Cannabis oil (15% cannabidiol and 4% THC) vs placebo oil
Withdrawals due to adverse events · Patients with active Crohn's disease
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Cannabis oil (5% cannabidiol sublingual oil) vs placebo oil
Withdrawals due to adverse events · Patients with active Crohn's disease
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Cannabidiol vs AMISULPRIDE
Adverse effects: measured adverse events ‐ medium term ‐ not measured · patients with schizophrenia
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Cannabidiol (10 mg/kg and 20 mg/kg) plus ASMs vs placebo plus ASMs
Number of participants with adverse events leading to study discontinuation · Lennox‐Gastaut syndrome, any age
Cannabidiol (10 mg/kg and 20 mg/kg) plus ASMs leads to higher number of participants with adverse events leading to study… compared with placebo plus ASMs (high certainty).
1 finding from 1 review
- RR 6.62 [1.56, 28.15]2 studies · 396 participantsHigh