Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

137 questions · 137 findings · 24 reviews · Headline outcomes only

No studies found 36 · 26.3%GRADE not reported 12 · 8.8%Very low 36 · 26.3%Low 30 · 21.9%Moderate 19 · 13.9%High 4 · 2.9%

CERA vs other ESA

Adverse events: hypertension · patients with the anaemia of end‐stage kidney disease undergoing dialysis

CERA showed no clear difference in numbers of adverse events due to hypertension: CERA every 2 weeks… compared with other ESA (high certainty).

1 finding from 1 review

CERA vs other ESA

Numbers of adverse events due to access thrombosis · patients with the anaemia of end‐stage kidney disease undergoing dialysis

CERA showed no clear difference in numbers of adverse events due to access thrombosis: CERA every 2… compared with other ESA (moderate certainty).

1 finding from 1 review

Impulsive lifestyle counselling + treatment‐as‐usual vs usual care

Adverse events:incarceration Assessed by: incarceration between a 3‐ and 9‐month · adults with antisocial personality disorder

It is very uncertain whether impulsive lifestyle counselling + treatment‐as‐usual changes adverse events:incarceration Assessed by: incarceration between a 3‐… compared with treatment‐as‐usual alone (very low certainty).

1 finding from 1 review