Adverse effects of antibiotics · children, aged 2 to 59 months, with WHO‐defined non‐severe pneumonia and wheeze
Antibiotic therapy showed no clear difference in treatment harms (adverse events or side effects associated with… compared with placebo compared to placebo (low certainty).
1 finding from 1 review
Adverse events · Ventilator‐associated pneumonia
Monotherapy showed no clear difference in adverse events compared with combination therapy (moderate certainty).
1 finding from 1 review
Adverse events · Ventilator‐associated pneumonia
Carbapenems showed no clear difference in adverse events compared with non‐carbapenems (low certainty).
1 finding from 1 review
Intervention not reported
Adverse events ( · children and adults with acute pneumonia
1 finding from 1 review
Allergic adverse events · adults receiving mechanical ventilation for at least 48 hours
It is very uncertain whether topical prophylaxis changes allergic adverse events compared with no topical prophylaxis (very low certainty).
1 finding from 1 review
Allergic adverse events · adults receiving mechanical ventilation for at least 48 hours
Topical plus systemic prophylaxis showed no clear difference in allergic adverse events compared with placebo or no treatment (low certainty).
1 finding from 1 review
Adverse events ‐ short term · people suspected to have meningococcal disease (adults and children)
1 finding from 1 review
Adverse events (ITT analysis) · group A streptococcal pharyngitis
It is very uncertain whether azithromycin changes adverse events (ITT analysis) compared with amoxicillin (very low certainty).
1 finding from 1 review
Adverse events (ITT analysis) · group A streptococcal pharyngitis
Carbacephem showed no clear difference in adverse events (ITT analysis) compared with penicillin (low certainty).
1 finding from 1 review
Adverse events (ITT analysis) · group A streptococcal pharyngitis
It is very uncertain whether cephalosporins changes adverse events (ITT analysis) compared with penicillin (very low certainty).
1 finding from 1 review
Adverse events (ITT analysis) · group A streptococcal pharyngitis
Macrolides showed no clear difference in adverse events (ITT analysis) compared with penicillin (low certainty).
1 finding from 1 review
Dropouts due to adverse events · adults receiving mechanical ventilation for at least 48 hours
It is very uncertain whether topical prophylaxis changes dropouts due to adverse events compared with no topical prophylaxis (very low certainty).
1 finding from 1 review
Dropouts due to adverse events · adults receiving mechanical ventilation for at least 48 hours
Topical plus systemic prophylaxis showed no clear difference in dropouts due to adverse events compared with placebo or no treatment (low certainty).
1 finding from 1 review
Serious adverse events maximum · neonates and children with hospital‐acquired pneumonia
It is very uncertain whether cefepime changes serious adverse events Maximum compared with ceftazidime (very low certainty).
1 finding from 1 review
Serious adverse events maximum · neonates and children with hospital‐acquired pneumonia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Gastrointestinal adverse events · adults receiving mechanical ventilation for at least 48 hours
Topical prophylaxis showed no clear difference in gastrointestinal adverse events compared with no topical prophylaxis (low certainty).
1 finding from 1 review
Gastrointestinal adverse events · adults receiving mechanical ventilation for at least 48 hours
Topical plus systemic prophylaxis showed no clear difference in gastrointestinal adverse events compared with placebo or no treatment (low certainty).
1 finding from 1 review
Non‐serious adverse events Maximum · neonates and children with hospital‐acquired pneumonia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Non‐serious adverse events Maximum · neonates and children with hospital‐acquired pneumonia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Incidence of adverse events ‐ overall · children with HIV infection aged 12 years and under
The intervention showed no clear difference in incidence of adverse events ‐ overall (moderate certainty).
1 finding from 1 review