Adverse events · Adults with aggressive periodontitis
Amoxicillin + clavulanate + SRP showed no clear difference in adverse events compared with tetracycline + SRP; GRADE not reported.
1 finding from 1 review
Adverse events · Adults with chronic periodontitis
It is very uncertain whether amoxicillin + clavulanate + SRP changes adverse events compared with SRP (very low certainty).
1 finding from 1 review
Adverse events · Adults with aggressive periodontitis
Amoxicillin + metronidazole + SRP showed no clear difference in adverse events compared with clarithromycin + SRP; GRADE not reported.
1 finding from 1 review
Adverse events · Adults with periodontitis (chronic and aggressive)
It is very uncertain whether amoxicillin + metronidazole + SRP changes adverse events compared with SRP (very low certainty).
1 finding from 1 review
Most common adverse events were mild gastrointestinal disturbances, nausea and vomiting, metallic taste, and diarrhoea in the intervention group. Control group reported adverse events like hypothermia, mild…
2 studies · 389 participants
Very low
Adverse events · Adults undergoing dental implant placement
Prophylactic systemic antibiotics (amoxicillin) showed no clear difference in adverse events compared with no antibiotics or placebo; GRADE not reported.
1 finding from 1 review
Adverse events due to periodontal therapy · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
It is very uncertain whether scaling and root planing (SRP) plus antibiotics (amoxicillin and… changes adverse events due to periodontal therapy compared with supragingival scaling (plus placebo) (very low certainty).
1 finding from 1 review
Adverse events · Adults with periodontitis (chronic and aggressive)
Metronidazole + SRP showed no clear difference in adverse events compared with amoxicillin + metronidazole + SRP; GRADE not reported.
1 finding from 1 review
All three included trials (Matarazzo 2008; Silva 2011; Xajigeorgiou 2006) reported adverse events in both MTZ + SRP and AMOX + MTZ + SRP groups (nausea, vomiting, diarrhoea, headache, metallic taste, irritability, mild…
3 studies · 84 participants
GRADE not reported
Adverse events · Adults with aggressive periodontitis
Doxycycline + SRP showed no clear difference in adverse events compared with amoxicillin + metronidazole + SRP; GRADE not reported.
1 finding from 1 review