Findings

What do systematic reviews say?

3 questions · 3 findings · 2 reviews · Sexually Transmitted Infections

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 66.7%Low 1 · 33.3%Moderate 0 · 0%High 0 · 0%

Erythromycin vs any other macrolide

Minor adverse events · sexually active adults

It is very uncertain whether macrolide (erythromycin) changes minor adverse events compared with any other macrolide (very low certainty).

1 finding from 1 review

Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults 2017 · Cochrane Headline outcomes only
RR 1.14 [0.63, 2.06]
1 study · 101 participants
Very low

Macrolides vs other antibiotics

Minor adverse events · sexually active adults

It is very uncertain whether macrolides changes minor adverse events compared with any other antibiotic (very low certainty).

1 finding from 1 review

Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults 2017 · Cochrane Headline outcomes only
RR 1.34 [0.24, 7.51]
3 studies · 412 participants
Very low

Regimens containing macrolides (azithromycin) vs regimens containing tetracycline (doxycycline)

Adverse events: any antibiotic‐related adverse event leading to discontinuation of therapy · women with PID

Regimens containing macrolides (azithromycin) showed no clear difference in adverse events: any antibiotic‐related adverse event leading to… compared with regimens containing tetracycline (doxycycline) (low certainty).

1 finding from 1 review

Antibiotic therapy for pelvic inflammatory disease 2020 · Cochrane Headline outcomes only
RR 0.71 [0.38, 1.34]
Studies not reported
Low