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Evidence found and GRADE certainty

1,199 questions · 1,226 findings · 451 reviews

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No studies found 289 · 23.6%GRADE not reported 121 · 9.9%Very low 350 · 28.5%Low 279 · 22.8%Moderate 139 · 11.3%High 48 · 3.9%

Intervention not reported

Adverse events: hypercalcaemia in trials using the active forms of vitamin D (alfacalcidol and calcitriol) ( · adults

The intervention may leads to higher adverse events: hypercalcaemia in trials using the active forms of… (low certainty).

1 finding from 1 review

Heated humidification + fixed CPAP vs fixed CPAP

Adverse events (machine tolerability outcomes) assessed as number of participants experiencing a blocked nose · adults with a diagnosis of sleep apnoea

Heated humidification + fixed CPAP may leads to lower adverse events (machine tolerability outcomes) assessed as number of… compared with fixed CPAP alone (low certainty).

1 finding from 1 review

Intervention not reported

Adverse outcome: unintended adverse events attributable to the intervention ATCS+, IVR, unidirectional versus various controls · participants at risk of under‐immunisation (children, adolescents and adults)

The review found no eligible studies for this question.

1 finding from 1 review

Rinse‐free hand wash vs control

Adverse skin reactions (within the study period) Calculated as: number of events Length of time observed: range = 5 to 8 months · children aged from birth to 14 years old

It is very uncertain whether rinse‐free hand wash changes adverse skin reactions (within the study period) Calculated as:… compared with control (very low certainty).

1 finding from 1 review

Live zoster vaccine vs placebo

Participants with adverse events: 1 or more serious adverse events regardless of type of storage of the vaccine Clinical or laboratory criteria · healthy older adults aged ≥ 60 years

Live zoster vaccine showed no clear difference in participants with adverse events: 1 or more serious adverse events… compared with placebo (moderate certainty).

1 finding from 1 review

Intervention not reported

Behavioural outcome: adherence to medication or composite outcome (medication adherence and rate of adverse events) ATCS Plus versus usual care · patients with various conditions or at risk of low adherence to medication or laboratory tests
1 finding from 1 review

Intervention not reported

Adverse outcome: unintended adverse events attributable to the intervention Multimodal/complex intervention, ATCS Plus, IVR versus various controls · participants at risk of developing long‐term conditions

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse outcome: unintended adverse events attributable to the intervention Multimodal/complex intervention, ATCS Plus, IVR, unidirectional versus various controls · participants at risk for breast, colorectal or cervical cancer; or osteoporosis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse outcome: unintended adverse events attributable to the intervention Multimodal/complex intervention, ATCS Plus, IVR, unidirectional versus various controls · patients with various conditions or at risk of low adherence to medication or laboratory tests

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse outcome: unintended adverse events attributable to the intervention Multimodal/complex intervention, ATCS Plus, IVR, unidirectional ATCS versus various controls · patients with hypertension

The review found no eligible studies for this question.

1 finding from 1 review