Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

127 questions · 131 findings · 83 reviews

No studies found 27 · 20.6%GRADE not reported 15 · 11.5%Very low 46 · 35.1%Low 23 · 17.6%Moderate 16 · 12.2%High 4 · 3.1%

iMRI image‐guided surgery vs surgery

Adverse events · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

5‐ALA image‐guided surgery vs surgery

Adverse events · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

Neuronavigation image‐guided surgery vs surgery

Adverse events · high‐grade glioma

The review found no eligible studies for this question.

2 findings from 2 reviews · compare the 2 reviews

Low dose naldemedine vs higher dose

Adverse events · people with cancer irrespective of whether receiving palliative care and with opioid‐induced bowel dysfunction

Low dose naldemedine showed no clear difference in adverse events compared with higher doses (low certainty).

1 finding from 1 review

Lower‐dose methylnaltrexone vs higher dose

Adverse events · people receiving palliative care irrespective of whether they had cancer with opioid‐induced bowel dysfunction

Methylnaltrexone lower dose showed no clear difference in adverse events compared with higher dose (low certainty).

1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Adverse events · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Intervention not reported

Adverse events · individuals without known diabetes mellitus but at high risk for the condition

The review found no eligible studies for this question.

1 finding from 1 review