Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,004 questions · 1,019 findings · 269 reviews

No studies found 333 · 32.7%GRADE not reported 106 · 10.4%Very low 313 · 30.7%Low 189 · 18.5%Moderate 66 · 6.5%High 12 · 1.2%

Rituximab/cyclosporin/prednisolone vs cyclosporin/prednisolone

Adverse events: hypotension · idiopathic steroid‐resistant nephrotic syndrome in children

It is very uncertain whether rituximab/cyclosporin/prednisolone changes adverse events: hypotension compared with cyclosporin/prednisolone (very low certainty).

1 finding from 1 review

Oral retinoids: alitretinoin 10 mg vs placebo

Primary outcome 3: Adverse events · people with moderate to severe chronic hand eczema

Oral retinoids: alitretinoin 10 mg showed no clear difference in primary: all adverse events compared with placebo (moderate certainty).

1 finding from 1 review

MDAC + hospital intervention vs SDAC + hospital intervention

Incidence of adverse events · first aid in patients with acute oral poisoning (carbamazepine, yellow oleander, or combinations of different drugs)

MDAC + hospital intervention may leads to higher incidence of adverse events compared with SDAC + hospital intervention (low certainty).

1 finding from 1 review

SDAC vs syrup of ipecac

Incidence of adverse events · first aid in patients with acute oral poisoning (anti‐inflammatory drugs, analgesics or psychotropic drugs)

It is very uncertain whether SDAC changes incidence of adverse events compared with syrup of ipecac (very low certainty).

1 finding from 1 review

MDAC + hospital intervention vs hospital intervention

Incidence of adverse events · first aid in patients with acute oral poisoning (benzodiazepines, yellow oleander or combinations of different drugs)

MDAC + hospital intervention showed no clear difference in incidence of adverse events compared with hospital intervention (low certainty).

1 finding from 1 review