Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,041 questions · 1,056 findings · 283 reviews

No studies found 346 · 32.8%GRADE not reported 111 · 10.5%Very low 326 · 30.9%Low 195 · 18.5%Moderate 66 · 6.3%High 12 · 1.1%

Azathioprine vs cyclophosphamide

Serious adverse events · adults with renal vasculitis for maintenance therapy

Azathioprine showed no clear difference in serious adverse events compared with cyclophosphamide (moderate certainty).

1 finding from 1 review

Mesalamine vs placebo

Serious adverse events · Patients with collagenous colitis

Mesalamine showed no clear difference in serious adverse events compared with placebo (low certainty).

1 finding from 1 review

Budesonide vs placebo

Serious adverse events · Patients with collagenous colitis

It is very uncertain whether budesonide changes serious adverse events compared with placebo (very low certainty).

1 finding from 1 review