Findings

What do systematic reviews say?

185 questions · 187 findings · 30 reviews

No studies found 32 · 17.1%GRADE not reported 4 · 2.1%Very low 58 · 31%Low 59 · 31.6%Moderate 29 · 15.5%High 5 · 2.7%

Adverse events · Patients with active Crohn's disease

Antibiotic showed no clear difference in adverse events compared with placebo (high certainty).

1 finding from 1 review

Antibiotics for induction and maintenance of remission in Crohn's disease 2019 · Cochrane Headline outcomes only
RR 0.87 [0.75, 1.02]
9 studies · 852 participants
High

Serious adverse events · Patients with active Crohn's disease

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for induction and maintenance of remission in Crohn's disease 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Serious adverse events · Patients with active Crohn's disease

Antibiotic showed no clear difference in serious adverse events compared with placebo (low certainty).

1 finding from 1 review

Antibiotics for induction and maintenance of remission in Crohn's disease 2019 · Cochrane Headline outcomes only
RR 1.7 [0.29, 10.01]
3 studies · 520 participants
Low

Withdrawals due to adverse events · Patients with active Crohn's disease

Antibiotic with anti‐TNF showed no clear difference in withdrawal due to adverse events compared with placebo with anti‐TNF (low certainty).

1 finding from 1 review

Antibiotics for induction and maintenance of remission in Crohn's disease 2019 · Cochrane Headline outcomes only
RR 0.82 [0.19, 3.45]
2 studies · 100 participants
Low

Withdrawals due to adverse events · Patients with active Crohn's disease

Antibiotic showed no clear difference in withdrawal due to adverse events compared with placebo (low certainty).

1 finding from 1 review

Antibiotics for induction and maintenance of remission in Crohn's disease 2019 · Cochrane Headline outcomes only
RR 0.86 [0.57, 1.29]
9 studies · 858 participants
Low