Findings

What do systematic reviews say?

6 questions · 6 findings · 5 reviews · Headline outcomes only

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No studies found 1 · 16.7%GRADE not reported 0 · 0%Very low 1 · 16.7%Low 4 · 66.7%Moderate 0 · 0%High 0 · 0%

Rice fortified with iron alone or in combination with other micronutrients vs unfortified rice (no micronutrients added)

Any adverse effects (hookworm infection risk) · general population of all age groups (including pregnant women) from any country, over two years of age

Rice fortified with iron alone or in combination with other… may leads to higher any adverse effects (hookworm infection risk) compared with unfortified rice (no micronutrients added) (low certainty).

1 finding from 1 review

Fortification of rice with vitamins and minerals for addressing micronutrient malnutrition 2019 · Cochrane Headline outcomes only
RR 1.78 [1.18, 2.7]
1 study · 785 participants
Low

CHOLINERGIC DRUGS vs placebo

Adverse effects: Any adverse events · patients with antipsychotic‐induced tardive dyskinesia

It is very uncertain whether CHOLINERGIC DRUGS changes adverse effects: Any adverse events compared with PLACEBO (very low certainty).

1 finding from 1 review

Cholinergic medication for antipsychotic‐induced tardive dyskinesia 2018 · Cochrane Headline outcomes only
RR 0.56 [0.15, 2.14]
4 studies · 106 participants
Very low

POLYPEPTIDE ‐ CERULETIDE vs placebo

Adverse effects ‐ any adverse effect · female and male 55‐59 year old (mean) patients with various psychiatric conditions and antipsychotic‐induced tardive dyskinesia

POLYPEPTIDE ‐ CERULETIDE showed no clear difference in adverse effects ‐ any adverse effect compared with PLACEBO (low certainty).

1 finding from 1 review

Miscellaneous treatments for antipsychotic‐induced tardive dyskinesia 2018 · Cochrane Headline outcomes only
RR 1.32 [0.74, 2.36]
2 studies · 122 participants
Low

Levetiracetam vs placebo

Adverse effects ‐ any adverse effect · patients with antipsychotic‐induced tardive dyskinesia

ANTIEPILEPTIC ‐ LEVETIRACETAM showed no clear difference in adverse effects ‐ any adverse effect compared with PLACEBO (low certainty).

1 finding from 1 review

Miscellaneous treatments for antipsychotic‐induced tardive dyskinesia 2018 · Cochrane Headline outcomes only
RR 0.51 [0.25, 1.04]
1 study · 69 participants
Low

Intervention not reported

Any other adverse effects · adults with Ménière's disease or syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Restriction of salt, caffeine and alcohol intake for the treatment of Ménière's disease or syndrome 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

S‐adenosyl methionine as monotherapy vs tricyclic antidepressants (TCAs)

Acceptability. Participants experiencing troublesome adverse effects of any nature · depression in adults

S‐adenosyl methionine as monotherapy may leads to lower acceptability. Participants experiencing troublesome adverse effects… compared with tricyclic antidepressant agent (low certainty).

1 finding from 1 review

S‐adenosyl methionine (SAMe) for depression in adults 2016 · Cochrane Headline outcomes only
RR 0.68 [0.52, 0.88]
3 studies · 604 participants
Low