Findings

What do systematic reviews say?

10 questions · 10 findings · 4 reviews · Headline outcomes only

Sort:Best matchNewest Highest certainty Download CSV

No studies found 1 · 10%GRADE not reported 0 · 0%Very low 6 · 60%Low 3 · 30%Moderate 0 · 0%High 0 · 0%

Saline vs no saline treatment

Other adverse effects: local irritation · allergic rhinitis

1 finding from 1 review

Saline irrigation for allergic rhinitis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Saline irrigation plus pharmacological treatment vs pharmacological treatment alone

Other adverse effects: local irritation · allergic rhinitis

1 finding from 1 review

Saline irrigation for allergic rhinitis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Saline irrigation plus pharmacological treatment vs pharmacological treatment alone

Adverse effects ‐ epistaxis · allergic rhinitis

1 finding from 1 review

Saline irrigation for allergic rhinitis 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Ear drops (water or saline) vs no treatment

Discomfort/pain · adults and children with ear wax requiring removal

Ear drops (water or saline) may leads to lower adverse effects: discomfort, irritation or pain compared with no treatment (low certainty).

1 finding from 1 review

Ear drops for the removal of ear wax 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Oropharyngeal colostrum (OPC) vs No treatment or saline or water

Reported adverse effects · preterm infants

1 finding from 1 review

Oropharyngeal colostrum in preventing mortality and morbidity in preterm infants 2018 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 335 participants
Very low

Injectional interferon alpha‐2B vs Normal saline

Treatment‐related adverse effects · men with chronic (≥ 12 months) Peyronie's disease (single plaque)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Injectional nicardipine vs Normal saline

Treatment‐related adverse effects · men with chronic Peyronie's disease (plaques without calcification)

It is very uncertain whether injectional nicardipine changes treatment‐related adverse effects compared with saline (very low certainty).

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
RR 2.82 [0.12, 66.62]
1 study · 62 participants
Very low

Injectional verapamil vs saline (short‐term)

Treatment‐related adverse effects · men with Peyronie's disease (palpable plaque or pain)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 14 participants
Very low

Injectional betamethasone vs Normal saline

Treatment‐related adverse effects (long‐term) · men with Peyronie's disease (not defined)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Very low

Ear drops (any active treatment) vs ear drops (water or saline)

Discomfort/pain · adults and children with ear wax requiring removal

Ear drops (any active treatment) may leads to lower adverse effects: discomfort, irritation or pain compared with ear drops (water or saline) (low certainty).

1 finding from 1 review

Ear drops for the removal of ear wax 2018 · Cochrane Headline outcomes only
no estimate extracted
10 participants
Low