Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

8 questions · 8 findings · 6 reviews · Schizophrenia

No studies found 1 · 12.5%GRADE not reported 0 · 0%Very low 4 · 50%Low 3 · 37.5%Moderate 0 · 0%High 0 · 0%

Pericyazine vs atypical antipsychotics

Adverse effects: any observed extrapyramidal symptoms ‐ short term (up to 6 months) · patients with schizophrenia

It is very uncertain whether pericyazine changes adverse Effects ‐ Extrapyramidal symptoms compared with atypical antipsychotic (very low certainty).

1 finding from 1 review

ELECTRIC ACUPUNCTURE CONVULSIVE THERAPY vs ECT

Adverse effects: Spinal fracture (short‐term) · patients with schizophrenia

ELECTRIC ACUPUNCTURE CONVULSIVE THERAPY may leads to lower adverse effects: Spinal fracture (short‐term) compared with ELECTROCONVULSIVE THERAPY (low certainty).

1 finding from 1 review

POLYPEPTIDE ‐ CERULETIDE vs placebo

Adverse effects ‐ any adverse effect · female and male 55‐59 year old (mean) patients with various psychiatric conditions and antipsychotic‐induced tardive dyskinesia

POLYPEPTIDE ‐ CERULETIDE showed no clear difference in adverse effects ‐ any adverse effect compared with PLACEBO (low certainty).

1 finding from 1 review

Switch to another antipsychotic vs antipsychotic cessation

Adverse effects: use of antiparkinsonism drugs · psychiatric patients (schizophrenia) with antipsychotic‐induced tardive dyskinesia

It is very uncertain whether switch to another antipsychotic changes adverse effects: use of antiparkinsonism drugs compared with antipsychotic cessation (very low certainty).

1 finding from 1 review