What do systematic reviews say?

Systemic aminocaproic acid vs placebo

Systemic aminocaproic acid probably leads to higher adverse effects: nausea or vomiting compared with placebo (moderate certainty).

• Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
  RR 8.6 [2.09, 35.5]
  3 studies · 131 participants
  Moderate

Topical aminocaproic acid vs placebo

The review found no eligible studies for this question.

• Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Surgery vs botulinum neurotoxin injections

• Interventions for infantile esotropia 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 101 participants
  Very low

Bilateral recession vs unilateral recession‐resection

• Interventions for infantile esotropia 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 118 participants
  Very low

Vitrectomy vs scleral buckling

Pars plana vitrectomy (PPV) may leads to higher adverse effects (cataract development, choroidal detachment,… compared with scleral buckling (low certainty).

• Pars plana vitrectomy versus scleral buckling for repairing simple rhegmatogenous retinal detachments 2019 · Cochrane Headline outcomes only
  OR 1.71
  1 participants
  Low