Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

46 questions · 46 findings · 12 reviews

No studies found 9 · 19.6%GRADE not reported 9 · 19.6%Very low 4 · 8.7%Low 21 · 45.7%Moderate 2 · 4.3%High 1 · 2.2%

Acupuncture vs sham

Number of participants reporting an adverse event · people with episodic migraine

Acupuncture showed no clear difference in number of participants reporting adverse effects compared with sham interventions (high certainty).

1 finding from 1 review

Acupuncture vs prophylactic drugs

Number of participants reporting an adverse event · people with episodic migraine

Acupuncture probably leads to lower number of participants reporting adverse effects compared with prophylactic drugs (moderate certainty).

1 finding from 1 review

Acupuncture vs STANDARD DOSE ANTIPSYCHOTICS

Adverse effects: any observed extrapyramidal symptoms ‐ short term (up to 6 months) · patients with schizophrenia

ACUPUNCTURE may leads to lower adverse effects: Extrapyramidal symptoms (short‐term) compared with STANDARD DOSE ANTIPSYCHOTICS (low certainty).

1 finding from 1 review

Acupuncture vs prophylactic drugs

Adverse effects (drop‐outs due to adverse effects4) · people with episodic migraine

Acupuncture probably leads to lower number of participants dropping out due to adverse effects compared with prophylactic drugs (moderate certainty).

1 finding from 1 review

Acupuncture vs sham

Adverse effects (drop‐outs due to adverse effects4) · people with episodic migraine

Acupuncture showed no clear difference in number of participants dropping out due to adverse effects compared with sham interventions (low certainty).

1 finding from 1 review

Acupuncture vs TCM DRUG

Adverse effects: Clinically important general adverse effect (no data) · patients with schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

Acupuncture at P6 point vs sham

Adverse effects · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults
1 finding from 1 review
  • Adverse effects: 33 participants (1 RCT, Zotelli 2014); very low certainty. The trial authors were unsure whether the reported adverse events (one control participant reported increased sweating) were due to…
    1 study · 33 participants
    Very low

Acupuncture at P6 point with sedation vs Sham (dummy) acupuncture with sedation

Adverse effects · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults

The review found no eligible studies for this question.

1 finding from 1 review

Manual acupuncture vs cisapride

Adverse effects Discomfort after treatment · patients with functional dyspepsia

It is very uncertain whether manual acupuncture changes adverse effects Discomfort after treatment compared with cisapride (very low certainty).

1 finding from 1 review

Summary of findings: needle acupuncture vs valproate

Nausea · participants with epilepsy (one included study only recruited children with absence epilepsy while another included study recruited both…

Summary of findings: needle acupuncture showed no clear difference in frequency of adverse effects ‐ nausea ( compared with valproate (low certainty).

1 finding from 1 review