Cochrane · systematic review · CD008487

Acupuncture for functional dyspepsia

Lan, L, Zeng, F, Liu, GJ, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

GutAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
17
current version
GRADE rated
17
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 8 · 47.1%Low 9 · 52.9%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Manual acupuncture compared with cisapride for functional dyspepsia

Population: patients with functional dyspepsia
3 questions
OutcomeEffectEvidenceStatus / GRADE
Symptom scores of FD Graded by 4 levels1
Manual acupuncture vs cisapride
RR 1.02 [0.91, 1.16]1 study · 90 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Adverse effects Discomfort after treatment
Manual acupuncture vs cisapride
RR 0.21 [0.07, 0.69]1 study · 90 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Frequency of FD symptoms Number of FD attacks per week
Manual acupuncture vs cisapride
RR 1.04 [0.75, 1.4]1 study · 90 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency

Manual acupuncture compared with domperidone for functional dyspepsia

Population: patients with functional dyspepsia
1 question
OutcomeEffectEvidenceStatus / GRADE
Symptom scores of FD Graded by 4 levels1
Manual acupuncture vs domperidone
RR 1.24 [0.97, 1.58]1 study · 62 participantsLow
Downgraded: risk of bias, imprecision

Manual‐electroacupuncture compared with domperidone for functional dyspepsia

Population: patients with functional dyspepsia
5 questions
OutcomeEffectEvidenceStatus / GRADE
Symptom scores of FD Graded by 4 levels1
Manual‐electroacupuncture vs domperidone
RR 1.14 [1, 1.3]1 study · 126 participantsVery low
Downgraded: risk of bias
Symptom scores of ulceration subtype Graded by 4 levels1
Manual‐electroacupuncture vs domperidone
RR 0.81 [0.26, 2.51]1 study · 126 participantsVery low
Downgraded: risk of bias, imprecision
Symptom scores of regurgitation subtype Graded by 4 levels1
Manual‐electroacupuncture vs domperidone
RR 0.89 [0.42, 1.86]1 study · 126 participantsVery low
Downgraded: risk of bias, imprecision
Symptom scores of dyskinesia subtype Graded by 4 levels1
Manual‐electroacupuncture vs domperidone
RR 1.2 [0.76, 1.89]1 study · 126 participantsVery low
Downgraded: risk of bias, imprecision
Symptom scores of nonspecific subtype Graded by 4 levels1
Manual‐electroacupuncture vs domperidone
RR 1.45 [0.77, 2.76]1 study · 126 participantsVery low
Downgraded: risk of bias, imprecision

Electroacupuncture compared with itopride for functional dyspepsia

Population: patients with functional dyspepsia
1 question
OutcomeEffectEvidenceStatus / GRADE
Symptom scores of FD Graded by 4 levels1
Electroacupuncture vs itopride
RR 1.11 [0.98, 1.27]1 study · 80 participantsLow
Downgraded: risk of bias, imprecision

Acupuncture compared with sham acupuncture for functional dyspepsia

Population: patients with functional dyspepsia
7 questions
OutcomeEffectEvidenceStatus / GRADE
FD symptom scores Graded by 4 levels1
Acupuncture vs sham acupuncture
no estimate extracted2 studies · 116 participantsLow
Downgraded: risk of bias, imprecision
FD symptom scores at
Acupuncture vs sham acupuncture
no estimate extracted2 studies · 116 participantsLow
Downgraded: risk of bias, imprecision
Nepean Dyspepsia Symptom Index
Acupuncture vs sham acupuncture
no estimate extracted2 studies · 128 participantsLow
Downgraded: risk of bias, imprecision
Nepean Dyspepsia Life Quality Index
Acupuncture vs sham acupuncture
no estimate extracted2 studies · 128 participantsLow
Downgraded: risk of bias
Nepean Dyspepsia Symptom Index at
Acupuncture vs sham acupuncture
no estimate extracted1 study · 60 participantsLow
Downgraded: risk of bias, imprecision
Nepean Dyspepsia Life Quality Index at
Acupuncture vs sham acupuncture
no estimate extracted1 study · 60 participantsLow
Downgraded: risk of bias
SF‐36 SF‐36 scale
Acupuncture vs sham acupuncture
no estimate extracted2 studies · 116 participantsLow
Downgraded: risk of bias, imprecision