Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

127 questions · 127 findings · 52 reviews

No studies found 65 · 51.2%GRADE not reported 26 · 20.5%Very low 20 · 15.7%Low 14 · 11%Moderate 2 · 1.6%High 0 · 0%

Hyperbaric oxygen therapy plus standard care (surgery, antibiotics, oral rinse) vs Standard care alone (surgery, antibiotics, oral rinse)

Adverse effects · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)

The review found no eligible studies for this question.

1 finding from 1 review

FATTY ACID ‐ ETHYL‐EPA vs placebo

Adverse effects: EPS: dystonia measured by average ESRS change scores · female and male 42 (mean) years old patients with schizophrenia or schizoaffective disorder and antipsychotic‐induced tardive dyskinesia

FATTY ACID ‐ ETHYL‐EPA showed no clear difference in adverse effects: EPS: dystonia measured by average ESRS change scores compared with PLACEBO (low certainty).

1 finding from 1 review

FATTY ACID ‐ ETHYL‐EPA vs placebo

Adverse effects: 2. Extrapyramidal ‐ akathisia · female and male 42 (mean) years old patients with schizophrenia or schizoaffective disorder and antipsychotic‐induced tardive dyskinesia

It is very uncertain whether FATTY ACID ‐ ETHYL‐EPA changes adverse effects: EPS: akathisia measured by average ESRS change scores compared with PLACEBO (very low certainty).

1 finding from 1 review

FATTY ACID ‐ ETHYL‐EPA vs placebo

Adverse effects: EPS: parkinsonism measured by average ESRS change scores · female and male 42 (mean) years old patients with schizophrenia or schizoaffective disorder and antipsychotic‐induced tardive dyskinesia

FATTY ACID ‐ ETHYL‐EPA showed no clear difference in adverse effects: EPS: parkinsonism measured by average ESRS change… compared with PLACEBO (low certainty).

1 finding from 1 review

Initiation of prophylactic therapy guided by colonoscopy vs initiation of prophylactic therapy immediately after surgery

Adverse effects ( · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes adverse effects ( compared with initiation of prophylactic therapy immediately after surgery (very low certainty).

1 finding from 1 review

Intensification of prophylactic therapy guided by colonoscopy vs intensification guided by clinical recurrence

Adverse effects ( · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

It is very uncertain whether intensification of prophylactic therapy guided by colonoscopy changes adverse effects ( compared with intensification guided by clinical recurrence (very low certainty).

1 finding from 1 review

Acupressure at P6 point with sea band plus sedation vs Sham (dummy) acupressure with sedation

Adverse effects · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults

The review found no eligible studies for this question.

1 finding from 1 review

Acupressure at P6 point with sea band vs sham

Adverse effects · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults

The review found no eligible studies for this question.

1 finding from 1 review

Acupuncture at P6 point vs sham

Adverse effects · People (older than four years) classified as having gagging that interfered with dental treatment; included trials enrolled adults
1 finding from 1 review
  • Adverse effects: 33 participants (1 RCT, Zotelli 2014); very low certainty. The trial authors were unsure whether the reported adverse events (one control participant reported increased sweating) were due to…
    1 study · 33 participants
    Very low