What do systematic reviews say?

Lithium vs ECT

The review found no eligible studies for this question.

• Lithium for acute mania 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Lithium vs all antimanic agents

Lithium showed no clear difference in acceptability: total withdrawals compared with all antimanic agents (high certainty).

• Lithium for acute mania 2019 · Cochrane Headline outcomes only
  OR 1.16 [0.89, 1.52]
  24 studies · 4201 participants
  High

Antidepressants vs any other pharmacological intervention

It is very uncertain whether antidepressants changes treatment acceptability ‐dropouts compared with any other pharmacological intervention (very low certainty).

• Antidepressant treatment for postnatal depression 2021 · Cochrane Headline outcomes only
  RR 1.74 [0.99, 3.06]
  Studies not reported
  Very low

Antidepressants vs psychological interventions

It is very uncertain whether antidepressants changes treatment acceptability ‐ dropouts compared with psychological interventions (very low certainty).

• Antidepressant treatment for postnatal depression 2021 · Cochrane Headline outcomes only
  RR 1.07 [0.24, 4.88]
  Studies not reported
  Very low

Antidepressants vs psychosocial interventions

It is very uncertain whether antidepressants changes treatment acceptability ‐ dropouts compared with psychosocial interventions (very low certainty).

• Antidepressant treatment for postnatal depression 2021 · Cochrane Headline outcomes only
  RR 1.94 [1.12, 3.35]
  Studies not reported
  Very low

Antidepressants vs placebo

Antidepressants showed no clear difference in treatment acceptability ‐ dropouts compared with placebo (low certainty).

• Antidepressant treatment for postnatal depression 2021 · Cochrane Headline outcomes only
  RR 1.1 [0.74, 1.64]
  Studies not reported
  Low

Tricyclic antidepressants vs placebo

The review found no eligible studies for this question.

• Pharmacological interventions for somatoform disorders in adults 2014 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

New‐generation antidepressants vs placebo

New‐generation antidepressants showed no clear difference in acceptability (all‐cause drop‐outs) compared with placebo (low certainty).

• Pharmacological interventions for somatoform disorders in adults 2014 · Cochrane Headline outcomes only
  RR 1.01 [0.64, 1.61]
  2 studies · 163 participants
  Low

Natural products vs placebo

Natural products showed no clear difference in acceptability (all‐cause drop‐outs4) compared with placebo (low certainty).

• Pharmacological interventions for somatoform disorders in adults 2014 · Cochrane Headline outcomes only
  RR 0.85 [0.4, 1.78]
  3 studies · 506 participants
  Low

Tricyclic antidepressants vs another medication

Tricyclic antidepressants showed no clear difference in acceptability (all‐cause drop‐outs4) compared with another medication (low certainty).

• Pharmacological interventions for somatoform disorders in adults 2014 · Cochrane Headline outcomes only
  RR 1.48 [0.59, 3.72]
  8 studies · 556 participants
  Low

Antidepressants vs a combination of medications

Antidepressants showed no clear difference in acceptability (all‐cause drop‐outs4) compared with a combination of medications (low certainty).

• Pharmacological interventions for somatoform disorders in adults 2014 · Cochrane Headline outcomes only
  RR 0.8 [0.25, 2.52]
  2 studies · 118 participants
  Low

Intervention not reported

• Fetal scalp stimulation for assessing fetal well‐being during labour 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 327 participants
  GRADE not reported

Intervention not reported

• Antidepressants for preventing postnatal depression 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 51 participants
  Very low

Intervention not reported

• Antidepressants for preventing postnatal depression 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 22 participants
  Very low

Misoprostol vs surgery

Misoprostol showed no clear difference in women's views/acceptability of method compared with surgery (moderate certainty).

• Medical treatments for incomplete miscarriage 2017 · Cochrane Headline outcomes only
  RR 1 [0.99, 1]
  9 studies · 3349 participants
  Moderate

Misoprostol vs expectant care

• Medical treatments for incomplete miscarriage 2017 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Intervention not reported

• Fetal scalp stimulation for assessing fetal well‐being during labour 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 50 participants
  GRADE not reported

Intervention not reported

• Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Low

Intervention not reported

• Paying for performance to improve the delivery of health interventions in low‐ and middle‐income countries 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Low

Laser enamel preparation alone (Er,Cr:YSGG or CO2 laser) vs Acid-etching (phosphoric acid)

Both laser and acid-etching preparation were well accepted by patients (VAS, P = 1.000; ungraded, single study).

• The clinical effects of laser preparation of tooth surfaces for fissure sealants placement: a systematic review and… 2019 All outcomes

  Clinical (in vivo pit-and-fissure sealant placement)
  Kumar 2016 (Er,Cr:YSGG laser vs acid-etching): patient acceptance scored on a visual analogue scale; both preparations well accepted, P = 1.000; no significant difference.
  1 study · 50 participants
  GRADE not reported