Findings

What do systematic reviews say?

8 questions · 8 findings · 2 reviews

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No studies found 3 · 37.5%GRADE not reported 0 · 0%Very low 2 · 25%Low 2 · 25%Moderate 0 · 0%High 1 · 12.5%

procaine vs placebo

cognitive function improvement in "healthy" elderly persons Wechsler's memory scale2 · "healthy" old persons and demented women

procaine may leads to higher cognitive function improvement in "healthy" elderly persons… compared with placebo (low certainty).

1 finding from 1 review

Procaine treatments for cognition and dementia 2008 · Cochrane Headline outcomes only
OR 12.71 [3.81, 42.42]
1 study · 81 participants
Low

procaine vs placebo

cognitive function improvement in demented women Wechsler's memory scale2 · "healthy" old persons and demented women

It is very uncertain whether procaine changes cognitive function improvement in demented women Wechsler's memory… compared with placebo (very low certainty).

1 finding from 1 review

Procaine treatments for cognition and dementia 2008 · Cochrane Headline outcomes only
OR 0.04 [0, 1.12]
1 study · 12 participants
Very low

procaine vs placebo

overall changes from baseline in "healthy persons7 ‐ not measured · "healthy" old persons and demented women

The review found no eligible studies for this question.

1 finding from 1 review

Procaine treatments for cognition and dementia 2008 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

procaine vs placebo

overall changes from baseline in demented women · "healthy" old persons and demented women

It is very uncertain whether procaine changes overall changes from baseline in demented women compared with placebo (very low certainty).

1 finding from 1 review

Procaine treatments for cognition and dementia 2008 · Cochrane Headline outcomes only
OR 0.04 [0, 0.83]
1 study · 12 participants
Very low

procaine vs placebo

total adverse events in "healthy" persons · "healthy" old persons and demented women

procaine may leads to higher total adverse events in "healthy" persons compared with placebo (low certainty).

1 finding from 1 review

Procaine treatments for cognition and dementia 2008 · Cochrane Headline outcomes only
OR 7.3 [2.13, 25.02]
2 studies · 415 participants
Low

Summary of findings table ‐ 14 mL 1% chloroprocaine paracervical block vs normal saline paracervical block

Pain with dilation ‐ not measured · women requesting a surgical abortion at seven to 12 weeks of gestation

The review found no eligible studies for this question.

1 finding from 1 review

Local anaesthesia for pain control in first trimester surgical abortion 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ 14 mL 1% chloroprocaine paracervical block vs normal saline paracervical block

Pain with aspirationa,b · women requesting a surgical abortion at seven to 12 weeks of gestation

1 finding from 1 review

Local anaesthesia for pain control in first trimester surgical abortion 2024 · Cochrane Headline outcomes only
no estimate extracted
1 study · 79 participants
High

Summary of findings table ‐ 14 mL 1% chloroprocaine paracervical block vs normal saline paracervical block

Pain during procedure ‐ not measured · women requesting a surgical abortion at seven to 12 weeks of gestation

The review found no eligible studies for this question.

1 finding from 1 review

Local anaesthesia for pain control in first trimester surgical abortion 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found