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What do systematic reviews say?

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Evidence found and GRADE certainty

90 questions · 91 findings · 2 reviews · Schizophrenia

No studies found 4 · 4.4%GRADE not reported 59 · 64.8%Very low 25 · 27.5%Low 3 · 3.3%Moderate 0 · 0%High 0 · 0%

Zuclopenthixol dihydrochloride vs placebo

Leaving the study early · patients with schizophrenia

It is very uncertain whether zuclopenthixol dihydrochloride changes leaving the study early (any reason) compared with placebo (very low certainty).

2 findings from 2 reviews · compare the 2 reviews

Zuclopenthixol dihydrochloride vs placebo

Adverse effects ‐ important extrapyramidal adverse effects · patients with schizophrenia

It is very uncertain whether zuclopenthixol dihydrochloride changes adverse effects: Clinically important general adverse effect… compared with placebo (very low certainty).

1 finding from 1 review