Serum or plasma zinc (in µmol/L) · general population of all age groups (including pregnant women) from any country, over two years of age
1 finding from 1 review
QoL of participants living with SCD and their caregivers · people with sickle cell disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects · people with sickle cell disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Frequency of hospitalization · people with sickle cell disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Frequency of sickle cell‐related complications: number of participants with completely healed leg ulcer ( · people with sickle cell disease
It is very uncertain whether zinc changes frequency of sickle cell‐related complications: number of… compared with placebo (very low certainty).
1 finding from 1 review
Haemoglobin status · people with sickle cell disease
Zinc may leads to higher haemoglobin status (g/dL) compared with placebo (low certainty).
1 finding from 1 review
Frequency of crisis · people with sickle cell disease
Zinc showed no clear difference in frequency of crisis compared with placebo (low certainty).
1 finding from 1 review
Severity of pain · people with sickle cell disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Progression to late AMD (neovascular AMD, geographic atrophy or both) · people with AMD
Zinc probably leads to lower progression to late AMD (neovascular AMD, geographic atrophy or both) compared with placebo (moderate certainty).
1 finding from 1 review
Progression to neovascular AMD · people with AMD
Zinc probably leads to lower progression to neovascular AMD compared with placebo (moderate certainty).
1 finding from 1 review
Progression to geographic atrophy · people with AMD
Zinc showed no clear difference in progression to geographic atrophy compared with placebo (moderate certainty).
1 finding from 1 review
Progression to visual loss (loss of 3 or more lines on logMAR chart) · people with AMD
Zinc showed no clear difference in progression to visual loss (loss of 3 or more lines on logMAR chart) compared with placebo (moderate certainty).
1 finding from 1 review
Quality of life · people with AMD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects · people with AMD
1 finding from 1 review
no estimate extracted
286 participants
Very low
Resource use and costs · people with AMD
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · adults with HIV infection
It is very uncertain whether zinc changes mortality compared with placebo (very low certainty).
1 finding from 1 review
Rate of diarrhoea · adults with HIV infection
It is very uncertain whether zinc changes rate of diarrhoea compared with placebo (very low certainty).
1 finding from 1 review
Change in CD4 count · adults with HIV infection
1 finding from 1 review
Change in viral load · adults with HIV infection
1 finding from 1 review
Zinc deficiency (as defined by authors, depending on age and gender) · general population of all age groups (including pregnant women) from any country, over two years of age
It is very uncertain whether foods fortified with zinc plus other micronutrients changes zinc deficiency (as defined by authors, depending on age and gender) compared with foods fortified with other micronutrients without zinc (very low certainty).
1 finding from 1 review