Vitamin K vs control
Time to cessation of bleeding · adults and children with cystic fibrosis
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Findings
What do systematic reviews say?
46 questions · 48 findings · 5 reviews · Cystic Fibrosis and Genetic Disorders
No studies found 29 · 60.4%GRADE not reported 1 · 2.1%Very low 7 · 14.6%Low 7 · 14.6%Moderate 4 · 8.3%High 0 · 0%
Vitamin K vs control
BMD Z score (lumbar spine) · adults and children with cystic fibrosis
1 finding from 1 review
- no estimate extracted1 study · 38 participantsVery low
Vitamin K vs control
QoL · adults and children with cystic fibrosis
The review found no eligible studies for this question.
2 findings from 1 review
- no estimate extractedStudies not reportedNo studies found
- no estimate extractedStudies not reportedNo studies found
Vitamin K vs control
Adverse events · adults and children with cystic fibrosis
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Vitamin K vs control
PIVKA II levels: change in PIVKA II (ng/mL) · adults and children with cystic fibrosis
1 finding from 1 review
- no estimate extracted1 study · 18 participantsVery low
Vitamin K vs control
Uncarboxylated osteocalcin: change in carboxylation of osteocalcin (% Glu‐OC) · adults and children with cystic fibrosis
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Vitamin D vs placebo
Serum 25-hydroxyvitamin D level · people with sickle cell disease
1 finding from 1 review
- no estimate extracted1 study · 37 participantsModerate
Vitamin D vs placebo
Total body BMD measured by DEXA (% change from baseline) · people with sickle cell disease
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Vitamin D vs placebo
Adverse events · people with sickle cell disease
Vitamin D showed no clear difference in adverse events compared with placebo (low certainty).
1 finding from 1 review
- RR 3.16 [0.14, 72.84]1 study · 37 participantsLow
Vitamin D vs placebo
Pain frequency or change in pain frequency · people with sickle cell disease
1 finding from 1 review
- no estimate extracted1 study · 37 participantsLow
Vitamin D vs placebo
Acute chest syndrome ( · people with sickle cell disease
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Vitamin D vs placebo
Respiratory infections · people with sickle cell disease
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Vitamin D vs placebo
HRQoL score (physical functioning) (change from baseline) · people with sickle cell disease
1 finding from 1 review
- no estimate extracted1 study · 37 participantsLow
Vitamin D 100,000 IU/month vs 12,000 IU/month
Serum 25-hydroxyvitamin D level · people with sickle cell disease
1 finding from 1 review
- no estimate extracted1 study · 57 participantsLow
Vitamin C 1400 mg plus vitamin E 800 mg vs placebo
Frequency of pain crises in the · adults with sickle cell disease (adults with homozygous SCA or sickle beta 0 thalassaemia SCD)
It is very uncertain whether vitamin C 1400 mg plus vitamin E 800 mg changes frequency of pain crisis compared with placebo (very low certainty).
1 finding from 1 review
- RR 1.18 [0.64, 2.18]1 study · 83 participantsVery low
Vitamin C 1400 mg plus vitamin E 800 mg vs placebo
Severity of pain (use of opioid analgesics) · adults with sickle cell disease (adults with homozygous SCA or sickle beta 0 thalassaemia SCD)
It is very uncertain whether vitamin C 1400 mg plus vitamin E 800 mg changes severity of pain (use of opioid analgesics) compared with placebo (very low certainty).
1 finding from 1 review
- RR 1.33 [0.4, 4.37]1 study · 83 participantsVery low
Vitamin C 1400 mg plus vitamin E 800 mg vs placebo
QoL of participants living with SCD and their caregivers · adults with sickle cell disease (adults with homozygous SCA or sickle beta 0 thalassaemia SCD)
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Vitamin C 1400 mg plus vitamin E 800 mg vs placebo
Adverse effects · adults with sickle cell disease (adults with homozygous SCA or sickle beta 0 thalassaemia SCD)
It is very uncertain whether vitamin C 1400 mg plus vitamin E 800 mg changes adverse effects compared with placebo (very low certainty).
1 finding from 1 review
- RR 0.56 [0.31, 1]1 study · 83 participantsVery low
Vitamin C 1400 mg plus vitamin E 800 mg vs placebo
Frequency of hospitalization · adults with sickle cell disease (adults with homozygous SCA or sickle beta 0 thalassaemia SCD)
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Vitamin C 1400 mg plus vitamin E 800 mg vs placebo
Acute chest syndrome ( · adults with sickle cell disease (adults with homozygous SCA or sickle beta 0 thalassaemia SCD)
It is very uncertain whether vitamin C 1400 mg plus vitamin E 800 mg changes frequency of sickle cell‐related complications: acute chest syndrome compared with placebo (very low certainty).
1 finding from 1 review
- RR 2.661 study · 83 participantsVery low