Acute chest syndrome ( · adults with sickle cell disease (adults with homozygous SCA or sickle beta 0 thalassaemia SCD)
It is very uncertain whether vitamin C 1400 mg plus vitamin E 800 mg changes frequency of sickle cell‐related complications: acute chest syndrome compared with placebo (very low certainty).
1 finding from 1 review
Haemoglobin status · adults with sickle cell disease (adults with homozygous SCA or sickle beta 0 thalassaemia SCD)
1 finding from 1 review
sUA reduction · participants with chronic gout and sUA level > 0.36mmol/L
1 finding from 1 review
Joint pain reduction ‐ not reported · participants with chronic gout and sUA level > 0.36mmol/L
The review found no eligible studies for this question.
1 finding from 1 review
Participant global assessment · participants with chronic gout and sUA level > 0.36mmol/L
The review found no eligible studies for this question.
1 finding from 1 review
Total adverse events · participants with chronic gout and sUA level > 0.36mmol/L
1 finding from 1 review
Tophus regression · participants with chronic gout and sUA level > 0.36mmol/L
The review found no eligible studies for this question.
1 finding from 1 review
Acute gout attacks · participants with chronic gout and sUA level > 0.36mmol/L
The review found no eligible studies for this question.
1 finding from 1 review
Withdrawals due to adverse events · participants with chronic gout and sUA level > 0.36mmol/L
1 finding from 1 review
Incidence: lung cancer · healthy people and healthy male physicians
Vitamin A showed no clear difference in incidence: lung cancer compared with placebo (high certainty).
1 finding from 1 review
Incidence: lung cancer ‐ women · healthy male physicians, period: 1997 to 2007 and female health professionals, period: 1998 to 2005
Vitamin C leads to higher incidence: lung cancer ‐ women compared with placebo (high certainty).
1 finding from 1 review
Mortality: lung cancer ‐ men · healthy male physicians, period: 1997 to 2007 and female health professionals, period: 1998 to 2005
Vitamin C showed no clear difference in mortality: lung cancer ‐ men compared with placebo (high certainty).
1 finding from 1 review
Adverse events · healthy male physicians, period: 1997 to 2007 and female health professionals, period: 1998 to 2005
1 finding from 1 review
no estimate extracted
1 study · 1 participants
High
Incidence: all cancers · healthy male physicians, period: 1997 to 2007 and female health professionals, period: 1998 to 2005
Vitamin C showed no clear difference in incidence: all cancers compared with placebo (high certainty).
1 finding from 1 review
Mortality: all cancers · healthy male physicians, period: 1997 to 2007 and female health professionals, period: 1998 to 2005
Vitamin C showed no clear difference in mortality: all cancers compared with placebo (high certainty).
1 finding from 1 review
Mortality: lung cancer · healthy people and healthy male physicians
Vitamin A showed no clear difference in mortality: lung cancer compared with placebo (high certainty).
1 finding from 1 review
Adverse events: yellowing of the skin · healthy people and healthy male physicians
Vitamin A leads to higher adverse events: yellowing of the skin compared with placebo (high certainty).
1 finding from 1 review
Adverse events: minor gastrointestinal symptoms · healthy people and healthy male physicians
Vitamin A leads to higher adverse events: minor gastrointestinal symptoms compared with placebo (high certainty).
1 finding from 1 review
Incidence: all cancers · healthy people and healthy male physicians
Vitamin A showed no clear difference in incidence: all cancers compared with placebo (high certainty).
1 finding from 1 review
Mortality: all cancers · healthy people and healthy male physicians
Vitamin A showed no clear difference in mortality: all cancers compared with placebo (high certainty).
1 finding from 1 review