Small‐for‐gestational age · pregnant women and their infants..
Meta-analysis of observational studies (higher vs lower maternal 25(OH)D) for Small for gestational age: OR 0.54 (95% CI 0.44 to 0.67), statistically significant. Umbrella review outcome-level evidence grade: Suggestive.
1 finding from 1 review
Pre‐eclampsia · pregnant women and their infants..
Meta-analysis of observational studies (higher vs lower maternal 25(OH)D) for Pre-eclampsia: OR 0.56 (95% CI 0.39 to 0.80), statistically significant. Umbrella review outcome-level evidence grade: No conclusion.
1 finding from 1 review
Head circumference (mm) · pregnant women and their infants..
Meta-analysis of observational studies (higher vs lower maternal 25(OH)D) for Head circumference: WMD 0.05 (95% CI -0.24 to 0.34), not statistically significant. Umbrella review outcome-level evidence grade: Suggestive.
1 finding from 1 review
Birth length · pregnant women and their infants..
Meta-analysis of observational studies (higher vs lower maternal 25(OH)D) for Birth length: WMD 0.19 (95% CI -0.26 to 0.65), not statistically significant. Umbrella review outcome-level evidence grade: Substantial effect unlikely.
1 finding from 1 review
Birthweight (g) · pregnant women and their infants..
Meta-analysis of observational studies (higher vs lower maternal 25(OH)D) for Birth weight: WMD 130.9 (95% CI 75.1 to 186.7), statistically significant. Umbrella review outcome-level evidence grade: Probable.
1 finding from 1 review
Gestational diabetes · pregnant women and their infants..
Meta-analysis of observational studies (higher vs lower maternal 25(OH)D) for Gestational diabetes: OR 0.67 (95% CI 0.53 to 0.85), statistically significant. Umbrella review outcome-level evidence grade: Suggestive.
1 finding from 1 review
sUA reduction · participants with chronic gout and sUA level > 0.36mmol/L
1 finding from 1 review
Joint pain reduction ‐ not reported · participants with chronic gout and sUA level > 0.36mmol/L
The review found no eligible studies for this question.
1 finding from 1 review
Participant global assessment · participants with chronic gout and sUA level > 0.36mmol/L
The review found no eligible studies for this question.
1 finding from 1 review
Total adverse events · participants with chronic gout and sUA level > 0.36mmol/L
1 finding from 1 review
Tophus regression · participants with chronic gout and sUA level > 0.36mmol/L
The review found no eligible studies for this question.
1 finding from 1 review
Acute gout attacks · participants with chronic gout and sUA level > 0.36mmol/L
The review found no eligible studies for this question.
1 finding from 1 review
Withdrawals due to adverse events · participants with chronic gout and sUA level > 0.36mmol/L
1 finding from 1 review
Incidence: lung cancer · healthy people and healthy male physicians
Vitamin A showed no clear difference in incidence: lung cancer compared with placebo (high certainty).
1 finding from 1 review
Incidence: lung cancer ‐ women · healthy male physicians, period: 1997 to 2007 and female health professionals, period: 1998 to 2005
Vitamin C leads to higher incidence: lung cancer ‐ women compared with placebo (high certainty).
1 finding from 1 review
Mortality: lung cancer ‐ men · healthy male physicians, period: 1997 to 2007 and female health professionals, period: 1998 to 2005
Vitamin C showed no clear difference in mortality: lung cancer ‐ men compared with placebo (high certainty).
1 finding from 1 review
Adverse events · healthy male physicians, period: 1997 to 2007 and female health professionals, period: 1998 to 2005
1 finding from 1 review
no estimate extracted
1 study · 1 participants
High
Incidence: all cancers · healthy male physicians, period: 1997 to 2007 and female health professionals, period: 1998 to 2005
Vitamin C showed no clear difference in incidence: all cancers compared with placebo (high certainty).
1 finding from 1 review
Mortality: all cancers · healthy male physicians, period: 1997 to 2007 and female health professionals, period: 1998 to 2005
Vitamin C showed no clear difference in mortality: all cancers compared with placebo (high certainty).
1 finding from 1 review
Mortality: lung cancer · healthy people and healthy male physicians
Vitamin A showed no clear difference in mortality: lung cancer compared with placebo (high certainty).
1 finding from 1 review