What do systematic reviews say?

Vasodilator vs placebo or no treatment

Vasodilator probably leads to higher vasodilator side effects compared with placebo or no treatment (moderate certainty).

• Vasodilators for women undergoing fertility treatment 2018 · Cochrane Headline outcomes only
  RR 2.35 [1.51, 3.66]
  4 studies · 418 participants
  Moderate

Vasodilator vs placebo or no treatment

Vasodilator showed no clear difference in live birth compared with placebo or no treatment (moderate certainty).

• Vasodilators for women undergoing fertility treatment 2018 · Cochrane Headline outcomes only
  RR 1.18 [0.83, 1.69]
  3 studies · 350 participants
  Moderate

Vasodilator vs placebo or no treatment

Vasodilator may leads to higher clinical pregnancy compared with placebo or no treatment (low certainty).

• Vasodilators for women undergoing fertility treatment 2018 · Cochrane Headline outcomes only
  RR 1.45 [1.19, 1.77]
  11 studies · 1054 participants
  Low

Vasodilator vs placebo or no treatment

• Vasodilators for women undergoing fertility treatment 2018 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 477 participants
  Very low

Vasodilator vs placebo or no treatment

Vasodilator showed no clear difference in multiple gestation or birth compared with placebo or no treatment (low certainty).

• Vasodilators for women undergoing fertility treatment 2018 · Cochrane Headline outcomes only
  RR 1.15 [0.55, 2.42]
  3 studies · 370 participants
  Low

Vasodilator vs placebo or no treatment

Vasodilator showed no clear difference in spontaneous miscarriage compared with placebo or no treatment (low certainty).

• Vasodilators for women undergoing fertility treatment 2018 · Cochrane Headline outcomes only
  RR 0.83 [0.37, 1.86]
  3 studies · 350 participants
  Low

Vasodilator vs placebo or no treatment

Vasodilator showed no clear difference in ectopic pregnancy compared with placebo or no treatment (low certainty).

• Vasodilators for women undergoing fertility treatment 2018 · Cochrane Headline outcomes only
  RR 1.48 [0.25, 8.69]
  2 studies · 250 participants
  Low