Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

14 questions · 14 findings · 2 reviews · Pregnancy and Childbirth

No studies found 1 · 7.1%GRADE not reported 3 · 21.4%Very low 2 · 14.3%Low 8 · 57.1%Moderate 0 · 0%High 0 · 0%

Vaginal misoprostol vs placebo

Opiate use (as a proxy measure for pain) for all participants on ITT (including those without confirmed AMI) · early fetal death (less than 24 weeks)

It is very uncertain whether vaginal misoprostol changes pain (opiate use) compared with placebo (very low certainty).

1 finding from 1 review