What do systematic reviews say?

Usual care vs immunosuppressive withdrawal after monotherapy

It is very uncertain whether usual care changes serious adverse events compared with immunosuppressive withdrawal after monotherapy (very low certainty).

• Withdrawal of immunosuppressant or biologic therapy for patients with quiescent Crohn's disease 2018 · Cochrane Headline outcomes only
  RR 3.29 [0.35, 30.8]
  2 studies · 134 participants
  Very low

Usual care vs immunosuppressive withdrawal after combination therapy

It is very uncertain whether usual care changes serious adverse events compared with immunosuppressive withdrawal after combination therapy (very low certainty).

• Withdrawal of immunosuppressant or biologic therapy for patients with quiescent Crohn's disease 2018 · Cochrane Headline outcomes only
  RR 1 [0.21, 4.66]
  1 study · 80 participants
  Very low

PPI plus usual care vs usual care alone or chronic obstructive pulmonary disease

The review found no eligible studies for this question.

• Proton pump inhibitors for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Usual care with ivabradine vs Placebo, no intervention or usual care (with or without placebo)

• Ivabradine as adjuvant treatment for chronic heart failure 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 270 participants
  Low
• Ivabradine as adjuvant treatment for chronic heart failure 2020 · Cochrane Headline outcomes only
  RR 0.96 [0.92, 1]
  2 studies · 17399 participants
  Moderate

Usual care with ivabradine vs Placebo, no intervention or usual care (with or without placebo)

• Ivabradine as adjuvant treatment for chronic heart failure 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 179 participants
  Low
• Ivabradine as adjuvant treatment for chronic heart failure 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Exercise plus usual pharmacological care vs usual pharmacological care alone

The review found no eligible studies for this question.

• Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Exercise plus usual pharmacological care vs another intervention (education, joint aids, or relaxation) plus usual pharmacological care

The review found no eligible studies for this question.

• Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Exercise plus usual pharmacological care vs placebo + standard care

The review found no eligible studies for this question.

• Exercise as adjunctive therapy for systemic lupus erythematosus 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found