Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

8 questions · 8 findings · 1 reviews · Eyes and Vision

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 6 · 75%Low 2 · 25%Moderate 0 · 0%High 0 · 0%

Transepithelial CXL using iontophoresis vs epithelium‐off CXL

Proportion of participants whose maximum K decreased by at least 2 diopters—at 24 months · participants with progressive keratoconus

It is very uncertain whether transepithelial CXL using iontophoresis changes proportion of participants whose maximum K decreased by at least 2… compared with epithelium‐off CXL (very low certainty).

1 finding from 1 review

Transepithelial CXL using iontophoresis vs epithelium‐off CXL

Proportion of participants whose maximum K increased by at least 2 diopters—at 24 months · participants with progressive keratoconus

It is very uncertain whether transepithelial CXL using iontophoresis changes proportion of participants whose maximum K increased by at least 2… compared with epithelium‐off CXL (very low certainty).

1 finding from 1 review

Transepithelial CXL using iontophoresis vs epithelium‐off CXL

Proportion of participants whose keratoconus remained stable—at 24 months · participants with progressive keratoconus

It is very uncertain whether transepithelial CXL using iontophoresis changes proportion of participants whose keratoconus remained stable—at 24… compared with epithelium‐off CXL (very low certainty).

1 finding from 1 review

Transepithelial CXL using iontophoresis vs epithelium‐off CXL

Proportion of participants who gained 10 or more logMAR letters from baseline · participants with progressive keratoconus

It is very uncertain whether transepithelial CXL using iontophoresis changes proportion of participants who gained 10 or more logMAR letters from… compared with epithelium‐off CXL (very low certainty).

1 finding from 1 review

Transepithelial CXL using iontophoresis vs epithelium‐off CXL

Proportion of participants who lost 10 or more logMAR letters from baseline · participants with progressive keratoconus

It is very uncertain whether transepithelial CXL using iontophoresis changes proportion of participants who lost 10 or more logMAR letters from… compared with epithelium‐off CXL (very low certainty).

1 finding from 1 review