Findings

What do systematic reviews say?

2 questions · 2 findings · 2 reviews · Pregnancy and Childbirth

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 0 · 0%High 1 · 50%

Tranexamic acid vs placebo/no treatment

Serious maternal morbidity or death · pregnant women undergoing vaginal or caesarean birth who received TA for the prevention of postpartum haemorrhage

1 finding from 1 review

Tranexamic acid for preventing postpartum haemorrhage 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1511 participants
Low

Standard care plus IV tranexamic acid vs placebo or usual care

Hysterectomy to control bleeding · women with primary postpartum haemorrhage following vaginal or caesarean birth

Standard care plus IV tranexamic acid showed no clear difference in surgical intervention to control bleeding: Hysterectomy compared with placebo or standard care alone (high certainty).

1 finding from 1 review

Antifibrinolytic drugs for treating primary postpartum haemorrhage 2018 · Cochrane Headline outcomes only
RR 0.95 [0.81, 1.12]
1 study · 20017 participants
High