Findings

What do systematic reviews say?

7 questions · 7 findings · 3 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 14.3%Low 3 · 42.9%Moderate 0 · 0%High 3 · 42.9%

All topical NSAIDs Local adverse events · adults with strains, sprains, or muscle pull

1 finding from 1 review

Topical NSAIDs for acute musculoskeletal pain in adults 2015 · Cochrane Headline outcomes only
no estimate extracted
42 studies · 6125 participants
High

All topical NSAIDs Systemic adverse events · adults with strains, sprains, or muscle pull

1 finding from 1 review

Topical NSAIDs for acute musculoskeletal pain in adults 2015 · Cochrane Headline outcomes only
no estimate extracted
38 studies · 5372 participants
High

All topical NSAIDs Withdrawals ‐ adverse events · adults with strains, sprains, or muscle pull

1 finding from 1 review

Topical NSAIDs for acute musculoskeletal pain in adults 2015 · Cochrane Headline outcomes only
no estimate extracted
42 studies · 5790 participants
High

Adverse events · Adults with lateral elbow pain

Topical NSAIDs showed no clear difference in adverse events compared with placebo (low certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
RR 1.55 [0.2, 12.14]
3 studies · 153 participants
Low

Serious adverse events · adults with strains, sprains, or muscle pull

1 finding from 1 review

Topical NSAIDs for acute musculoskeletal pain in adults 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Withdrawals due to adverse events · Adults with lateral elbow pain

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs (NSAIDs) for treating lateral elbow pain in adults 2013 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 185 participants
Low

Adverse drug events · analgesia in traumatic corneal abrasions

It is very uncertain whether topical NSAIDs changes drug‐related adverse events compared with control (very low certainty).

1 finding from 1 review

Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions 2017 · Cochrane Headline outcomes only
RR 2.95 [0.32, 27.6]
2 studies · 163 participants
Very low