Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

11 questions · 11 findings · 4 reviews

No studies found 2 · 18.2%GRADE not reported 0 · 0%Very low 1 · 9.1%Low 5 · 45.5%Moderate 3 · 27.3%High 0 · 0%

Tacrolimus 0.1% vs vehicle

Primary: adverse events ‐ burning/itching at application site · people with moderate to severe nickel sulphate‐induced allergic contact dermatitis based on clinical history (hand eczema) and proven by…

Topical calcineurin inhibitors: tacrolimus 0.1% ointment showed no clear difference in primary: adverse events ‐ burning/itching at application site compared with vehicle (moderate certainty).

1 finding from 1 review