Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

634 questions · 675 findings · 72 reviews

No studies found 155 · 23%GRADE not reported 50 · 7.4%Very low 144 · 21.3%Low 166 · 24.6%Moderate 119 · 17.6%High 41 · 6.1%

Intensification of prophylactic therapy guided by colonoscopy vs intensification guided by clinical recurrence

Endoscopic recurrence · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

Intensification of prophylactic therapy guided by colonoscopy may leads to lower endoscopic recurrence ( compared with intensification guided by clinical recurrence (low certainty).

1 finding from 1 review

Intensification of prophylactic therapy guided by colonoscopy vs intensification guided by clinical recurrence

Adverse effects ( · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

It is very uncertain whether intensification of prophylactic therapy guided by colonoscopy changes adverse effects ( compared with intensification guided by clinical recurrence (very low certainty).

1 finding from 1 review

Intensive glycaemic control vs conventional glucose control

All‐cause mortality · patients with type 2 diabetes mellitus

Intensive glycaemic control showed no clear difference in mortality compared with standard glycaemic control (moderate certainty).

2 findings from 2 reviews · compare the 2 reviews

Intensive glycaemic control vs conventional glucose control

Cardiovascular mortality · patients with type 2 diabetes mellitus

Intensive glycaemic control showed no clear difference in cardiovascular mortality compared with conventional glycaemic control (moderate certainty).

1 finding from 1 review

Intensive glycaemic control vs conventional glucose control

Non‐fatal MI · patients with type 2 diabetes mellitus

Intensive glycaemic control probably leads to lower non‐fatal myocardial infarction compared with conventional glycaemic control (moderate certainty).

1 finding from 1 review

Intensive glycaemic control vs conventional glucose control

End‐stage renal disease · patients with type 2 diabetes mellitus

Intensive glycaemic control showed no clear difference in end‐stage renal disease compared with conventional glycaemic control (moderate certainty).

1 finding from 1 review

Combination of manual therapy and exercise following joint distension vs sham ultrasound following joint distension

Global assessment of treatment success · patients with adhesive capsulitis (frozen shoulder)

Combination of manual therapy and exercise following joint distension leads to higher global assessment of treatment success "Success, much improved,… compared with sham ultrasound following joint distension (high certainty).

1 finding from 1 review

Combination of manual therapy and exercise following joint distension vs sham ultrasound following joint distension

Adverse events · patients with adhesive capsulitis (frozen shoulder)

Combination of manual therapy and exercise following joint distension leads to lower adverse events compared with sham ultrasound following joint distension (high certainty).

1 finding from 1 review