Findings

What do systematic reviews say?

7 questions · 7 findings · 3 reviews

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No studies found 1 · 14.3%GRADE not reported 1 · 14.3%Very low 5 · 71.4%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Surgery plus radiotherapy vs Radiotherapy alone

Adverse events associated with treatment · Adults with oral cavity or oropharyngeal cancer

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
Adverse events: severe acute effects in both groups (subcutaneous fibrosis, telangiectasia, moderate-to-severe oedema, xerostomia, trismus, dysphagia); subcutaneous fibrosis more prevalent with surgery + radiotherapy…
1 study · 35 participants
Very low

Decompressive surgery plus radiotherapy vs radiotherapy

Adverse events · adults with metastatic extradural spinal cord compression (fit for surgery, paraplegic less than 48 hours, and without multiple discrete…

1 finding from 1 review

Interventions for the treatment of metastatic extradural spinal cord compression in adults 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 101 participants
GRADE not reported

Surgery plus whole brain radiotherapy (WBRT) vs stereotactic radiosurgery

Adverse events · people with single or solitary brain metastasis

It is very uncertain whether surgery plus whole brain radiotherapy (WBRT) changes adverse events compared with stereotactic radiosurgery (very low certainty).

1 finding from 1 review

Surgery versus stereotactic radiotherapy for people with single or solitary brain metastasis 2018 · Cochrane Headline outcomes only
RR 0.31 [0.07, 1.44]
1 study · 64 participants
Very low

Surgery plus radiotherapy vs Chemotherapy (chemoradiotherapy)

Adverse events associated with treatment · Adults with oral cavity or oropharyngeal cancer

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
Adverse events: not reported for any participants (Iyer 2015).
0 studies
No studies found

Surgery plus whole brain radiotherapy (WBRT) vs stereotactic radiosurgery

Adverse events (severe) · people with single or solitary brain metastasis

It is very uncertain whether surgery plus whole brain radiotherapy (WBRT) changes adverse events (severe) compared with stereotactic radiosurgery (very low certainty).

1 finding from 1 review

Surgery versus stereotactic radiotherapy for people with single or solitary brain metastasis 2018 · Cochrane Headline outcomes only
RR 0.13 [0, 2.5]
1 study · 64 participants
Very low

Surgery plus whole brain radiotherapy (WBRT) vs stereotactic radiosurgery

Adverse events (moderate) · people with single or solitary brain metastasis

It is very uncertain whether surgery plus whole brain radiotherapy (WBRT) changes adverse events (moderate) compared with stereotactic radiosurgery (very low certainty).

1 finding from 1 review

Surgery versus stereotactic radiotherapy for people with single or solitary brain metastasis 2018 · Cochrane Headline outcomes only
RR 0.62 [0.11, 3.5]
1 study · 64 participants
Very low

Surgery plus whole brain radiotherapy (WBRT) vs stereotactic radiosurgery plus WBRT

Adverse events (moderate) · people with single or solitary brain metastasis

It is very uncertain whether surgery plus whole brain radiotherapy (WBRT) changes adverse events (moderate) compared with stereotactic radiosurgery plus WBRT (very low certainty).

1 finding from 1 review

Surgery versus stereotactic radiotherapy for people with single or solitary brain metastasis 2018 · Cochrane Headline outcomes only
RR 0.37 [0.05, 2.98]
1 study · 21 participants
Very low