Findings

What do systematic reviews say?

557 questions · 600 findings · 75 reviews

Sort:Best matchNewest Highest certainty Download CSV

No studies found 188 · 31.3%GRADE not reported 62 · 10.3%Very low 154 · 25.7%Low 122 · 20.3%Moderate 62 · 10.3%High 12 · 2%

Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone

Adverse events · people with venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone

Pain · people with venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review

Subfascial endoscopic perforator surgery (SEPS) for treating venous leg ulcers 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) vs WBRT

Overall survival · Patients with brain metastases

Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) showed no clear difference in overall survival compared with WBRT (moderate certainty).

1 finding from 1 review

Whole brain radiation therapy (WBRT) alone versus WBRT and radiosurgery for the treatment of brain metastases 2017 · Cochrane Headline outcomes only
HR 0.82 [0.65, 1.02]
2 studies · 358 participants
Moderate

Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) vs WBRT

Disease‐specific survival · Patients with brain metastases

Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) showed no clear difference in disease‐specific survival compared with WBRT (moderate certainty).

1 finding from 1 review

Whole brain radiation therapy (WBRT) alone versus WBRT and radiosurgery for the treatment of brain metastases 2017 · Cochrane Headline outcomes only
RR 0.92 [0.64, 1.32]
1 study · 286 participants
Moderate

Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) vs WBRT

Local tumor control · Patients with brain metastases

Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) probably leads to lower local tumor control compared with WBRT (moderate certainty).

1 finding from 1 review

Whole brain radiation therapy (WBRT) alone versus WBRT and radiosurgery for the treatment of brain metastases 2017 · Cochrane Headline outcomes only
HR 0.27 [0.14, 0.52]
2 studies · 129 participants
Moderate

Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) vs WBRT

Functionally independent survival (KPS) · Patients with brain metastases

Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) showed no clear difference in functionally independent survival (KPS) compared with WBRT (moderate certainty).

1 finding from 1 review

Whole brain radiation therapy (WBRT) alone versus WBRT and radiosurgery for the treatment of brain metastases 2017 · Cochrane Headline outcomes only
RR 0.78 [0.61, 1]
1 study · 145 participants
Moderate

Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) vs WBRT

Steroid use · Patients with brain metastases

Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) may leads to lower steroid use compared with WBRT (low certainty).

1 finding from 1 review

Whole brain radiation therapy (WBRT) alone versus WBRT and radiosurgery for the treatment of brain metastases 2017 · Cochrane Headline outcomes only
RR 0.64 [0.42, 0.97]
1 study · 118 participants
Low

Summary of findings for nasal irrigation with topical steroids plus sinus surgery vs nasal irrigation with topical steroids alone

Change in QoL SNOT‐20 · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis

1 finding from 1 review

Surgery for nasal polyposis in cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 28 participants
Very low

Summary of findings for nasal irrigation with topical steroids plus sinus surgery vs nasal irrigation with topical steroids alone

FEV1 % predicted: absolute change from baseline · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis

1 finding from 1 review

Surgery for nasal polyposis in cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 28 participants
Very low

Summary of findings for nasal irrigation with topical steroids plus sinus surgery vs nasal irrigation with topical steroids alone

Eradication of bacterial infection · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis

1 finding from 1 review

Surgery for nasal polyposis in cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 28 participants
Very low

Summary of findings for nasal irrigation with topical steroids plus sinus surgery vs nasal irrigation with topical steroids alone

Clinical improvement(visual analogue scale) · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis

1 finding from 1 review

Surgery for nasal polyposis in cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 28 participants
Very low

Summary of findings for nasal irrigation with topical steroids plus sinus surgery vs nasal irrigation with topical steroids alone

Pulmonary exacerbations · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis

1 finding from 1 review

Surgery for nasal polyposis in cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 28 participants
Very low

Summary of findings for nasal irrigation with topical steroids plus sinus surgery vs nasal irrigation with topical steroids alone

All‐cause mortality · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis

The review found no eligible studies for this question.

1 finding from 1 review

Surgery for nasal polyposis in cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Surgery plus radiotherapy vs Chemotherapy (chemoradiotherapy)

Disease-free survival · Adults with oral cavity or oropharyngeal cancer

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
oral cavity
Disease-free survival: not reported (Iyer 2015).
0 studies
No studies found

Surgery plus radiotherapy vs Chemotherapy (chemoradiotherapy)

Total mortality · Adults with oral cavity or oropharyngeal cancer

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
oral cavity
Total mortality: study reported survival significantly better with surgery and RT vs chemoradiotherapy, but no useable data; 32 participants (1 RCT, Iyer 2015 oral cavity subgroup).
1 study · 32 participants
Very low

Surgery plus radiotherapy vs Chemotherapy (chemoradiotherapy)

Adverse events associated with treatment · Adults with oral cavity or oropharyngeal cancer

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
Adverse events: not reported for any participants (Iyer 2015).
0 studies
No studies found

Surgery plus radiotherapy vs Chemotherapy (chemoradiotherapy)

Recurrence · Adults with oral cavity or oropharyngeal cancer

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
oral cavity
Recurrence: not reported for the oral cancer subgroup (Iyer 2015).
0 studies
No studies found

Surgery plus radiotherapy vs Chemotherapy (chemoradiotherapy)

Locoregional recurrence · Adults with oral cavity or oropharyngeal cancer

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes
oral cavity
Locoregional recurrence: reported difference between groups not statistically significant (P=0.355), but no useable data; 32 participants (1 RCT, Iyer 2015).
1 study · 32 participants
Very low

Breastfeeding (post cleft-lip surgery) vs Spoon-feeding

Weight (kg) · Infants up to 6 months (from term) born with cleft lip, cleft palate or cleft lip and palate (Pierre Robin sequence or other syndromes…

Breastfeeding (post cleft-lip surgery) led to higher weight (kg) compared with spoon-feeding; GRADE not reported.

1 finding from 1 review

Feeding interventions for growth and development in infants with cleft lip, cleft palate or cleft lip and palate 2011 · Cochrane All outcomes
6 weeks post-surgery
MD 0.47 [0.20, 0.74]
1 study · 40 participants
GRADE not reported

Breastfeeding (post cleft-lip surgery) vs Spoon-feeding

Length of hospital stay · Infants up to 6 months (from term) born with cleft lip, cleft palate or cleft lip and palate (Pierre Robin sequence or other syndromes…

1 finding from 1 review

Feeding interventions for growth and development in infants with cleft lip, cleft palate or cleft lip and palate 2011 · Cochrane All outcomes
post-surgery
Duration of hospital stay (days): no statistically significant difference between the two groups (Darzi 1996); no pooled estimate displayed (totals not selected).
1 study · 40 participants
GRADE not reported