Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

557 questions · 600 findings · 75 reviews

No studies found 188 · 31.3%GRADE not reported 62 · 10.3%Very low 154 · 25.7%Low 122 · 20.3%Moderate 62 · 10.3%High 12 · 2%

Surgery vs non‐surgical treatment

Global assessment of treatment success · people with full‐thickness rotator cuff tears

Surgery showed no clear difference in participant‐rated global assessment of treatment success at 12 months compared with non‐operative treatment (low certainty).

1 finding from 1 review

Surgery vs oral medication

Control of bleeding (cure or improvement to acceptable level) At 2 years · women with heavy menstrual bleeding

Surgery probably leads to higher control of bleeding (cure or improvement to acceptable level) At 4… compared with oral medication (moderate certainty).

3 findings from 1 review

Surgery vs LNG‐IUS

Proportion of women with adverse events Endometrial ablation versus LNG‐IUS. At one year · women with heavy menstrual bleeding

Surgery probably leads to lower proportion of women with adverse events Endometrial ablation versus… compared with LNG‐IUS (moderate certainty).

1 finding from 1 review

Surgery vs oral medication

Overall satisfaction with treatment At 5 years · women with heavy menstrual bleeding

It is very uncertain whether surgery changes overall satisfaction with treatment At 5 years compared with oral medication (very low certainty).

1 finding from 1 review

Surgery vs LNG‐IUS

Objective control of bleeding: menstrual loss under 80 ml per cycle LNG‐IUS versus hysterectomy At 1 year · women with heavy menstrual bleeding

Surgery probably leads to higher objective control of bleeding: menstrual loss under 80 ml per cycle… compared with LNG‐IUS (moderate certainty).

1 finding from 1 review

Surgery vs LNG‐IUS

Subjective control of bleeding: PBAC no more than 75 per cycle Endometrial resection or ablation versus LNG‐IUS At 1 year · women with heavy menstrual bleeding

Surgery may leads to higher subjective control of bleeding: PBAC no more than 75 per cycle… compared with LNG‐IUS (low certainty).

1 finding from 1 review

Radiosurgery alone vs WBRT and radiosurgery

1‐Year radiosurgery‐targeted lesion controlNo. of participants: 602(4 RCTs) · patients with newly diagnosed multiple brain metastases

Radiosurgery alone leads to higher 1‐Year radiosurgery‐targeted lesion controlNo. of participants:… compared with WBRT and radiosurgery (high certainty).

1 finding from 1 review