What do systematic reviews say?

Summary of findings ‐ Prophylactic vs 'as required' anti‐staphylococcal antibiotics

Summary of findings ‐ Prophylactic showed no clear difference in number of people needing additional antibiotics compared with 'as required' anti‐staphylococcal antibiotics (low certainty).

• Prophylactic anti‐staphylococcal antibiotics for cystic fibrosis 2020 · Cochrane Headline outcomes only
  OR 0.18 [0.01, 3.6]
  1 study · 119 participants
  Low

Summary of findings ‐ Prophylactic vs 'as required' anti‐staphylococcal antibiotics

• Prophylactic anti‐staphylococcal antibiotics for cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 119 participants
  Low

Summary of findings ‐ Prophylactic vs 'as required' anti‐staphylococcal antibiotics

Summary of findings ‐ Prophylactic may leads to lower number of people with one or more isolates of S aureus (sensitive… compared with 'as required' anti‐staphylococcal antibiotics (low certainty).

• Prophylactic anti‐staphylococcal antibiotics for cystic fibrosis 2020 · Cochrane Headline outcomes only
  OR 0.21 [0.13, 0.35]
  3 studies · 315 participants
  Low

Summary of findings ‐ Prophylactic vs 'as required' anti‐staphylococcal antibiotics

Summary of findings ‐ Prophylactic showed no clear difference in number of people with one or more isolates of P aeruginosa compared with 'as required' anti‐staphylococcal antibiotics (low certainty).

• Prophylactic anti‐staphylococcal antibiotics for cystic fibrosis 2020 · Cochrane Headline outcomes only
  OR 0.74 [0.45, 1.23]
  3 studies · 312 participants
  Low

Summary of findings ‐ Prophylactic vs 'as required' anti‐staphylococcal antibiotics

• Prophylactic anti‐staphylococcal antibiotics for cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 140 participants
  Low

Summary of findings ‐ Prophylactic vs 'as required' anti‐staphylococcal antibiotics

The review found no eligible studies for this question.

• Prophylactic anti‐staphylococcal antibiotics for cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings ‐ Prophylactic vs 'as required' anti‐staphylococcal antibiotics

• Prophylactic anti‐staphylococcal antibiotics for cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 119 participants
  Low