Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

6 questions · 6 findings · 5 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 33.3%Moderate 3 · 50%High 1 · 16.7%

Statins vs Control at 4 months (3 ‐ 6 months)

Combined outcome of non‐fatal myocardial infarction, non‐fatal stroke, and total number of deaths · patients with acute coronary syndrome

Statins showed no clear difference in combined outcome of non‐fatal myocardial infarction, non‐fatal… compared with control at 4 months (3 to 6 months) (moderate certainty).

1 finding from 1 review

Perioperative statins vs placebo or no treatment

All cardiovascular death · participants with improving outcomes during and after noncardiac vascular surgery.

Perioperative statins showed no clear difference in death from cardiovascular causes compared with placebo or no treatment (low certainty).

1 finding from 1 review

Statins vs placebo

Death · 17,802 patients with low to normal levels of low density lipoprotein (LDL) cholesterol (< 130 mg/dL)

Statin probably leads to lower death compared with placebo (moderate certainty).

1 finding from 1 review

Statins vs placebo

All cardiovascular death · patients with aortic valve stenosis

Statin showed no clear difference in death from cardiovascular cause compared with placebo (low certainty).

1 finding from 1 review