Caries prevention (preventive fraction, SDF vs GIC+5% fluoride varnish) · intellectually disabled individuals with caries in permanent posterior teeth
SDF had a 45% preventative fraction versus glass ionomer cement plus fluoride varnish; no pooled estimate or GRADE rating was reported.
1 finding from 1 review
Caries arrest · Children and adults (with or without carious lesions)
Silver diamine fluoride (SDF) plus fluoride varnish showed no clear difference in caries arrest compared with sealants plus fluoride varnish (with or without restorations) (low certainty).
1 finding from 1 review
Secondary prevention of caries · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Primary caries prevention · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Oral health-related quality of life · Children with dental caries
SDF had no significant effect on oral health-related quality of life versus pooled standard-of-care caries treatments (SMD -0.06, 95% CI -0.20 to 0.08; ungraded).
1 finding from 1 review
Arrest of dentine caries · Preschool children with active dentine caries in primary teeth (mean age 3.4-4.0 years)
Silver diamine fluoride was about 2.5 times more likely than sodium fluoride to arrest dentine caries surfaces at 18 months (pooled OR 2.51, 95% CI 1.25 to 5.10; 2 RCTs), although between-study heterogeneity was high (I2=90.3%); certainty of evidence was not formally graded.
2 findings from 1 review
Secondary prevention of caries · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Primary caries prevention · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Primary caries prevention · Children and adults (with or without carious lesions)
It is very uncertain whether silver diamine fluoride (SDF) changes primary caries prevention compared with fluoride varnish (very low certainty).
3 findings from 1 review
MD -0.20 [-0.91, 0.51]
1 study · 100 participants
Very low
OR 0.95 [0.44, 2.05]
1 study · 237 participants
Very low
MD 0.00 [-0.26, 0.26]
1 study · 434 participants
Low
Secondary prevention of caries · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
3 findings from 1 review
No studies reported data in this dentition type
0 studies
No studies found
MD 0.04 [-0.30, 0.38]
1 study · 309 participants
Very low
No studies reported data in this dentition type
0 studies
No studies found
Primary caries prevention · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Secondary prevention of caries · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Caries arrest · Children and adults (with or without carious lesions)
It is very uncertain whether silver diamine fluoride (SDF) changes caries arrest compared with glass ionomer cement (GIC) plus fluoride varnish (very low certainty).
1 finding from 1 review
Caries arrest · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
3 findings from 1 review
No studies reported data in this dentition type
0 studies
No studies found
No studies reported data in this dentition type
0 studies
No studies found
MD -0.13 [-0.87, 0.61]
1 study · 309 participants
Very low
Caries arrest · Children and adults (with or without carious lesions)
Silver diamine fluoride (SDF) showed no clear difference in caries arrest compared with silver nitrate plus fluoride varnish (low certainty).
1 finding from 1 review
Caries arrestment at the tooth level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition)
In one trial, SDF increased tooth-level caries arrestment versus 5% sodium fluoride varnish (OR 4.75; ungraded subgroup).
1 finding from 1 review
Caries arrestment at the surface level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition)
Pooling two highly heterogeneous trials, SDF showed no significant difference versus 5% sodium fluoride varnish in surface-level caries arrestment (OR 1.46; ungraded subgroup).
1 finding from 1 review
Caries arrestment at the tooth level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition)
SDF probably results in a slight increase in tooth-level caries arrestment versus other methods (moderate certainty).
1 finding from 1 review
Caries arrestment at the surface level · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition)
SDF probably makes little to no difference to surface-level caries arrestment versus other methods (moderate certainty).
1 finding from 1 review
Caries arrest · Children (age 1-10 years) with active cavitated dentin caries lesions in primary molars
SDF is effective in arresting caries progression in cavitated primary molars overall (pooled ES 0.33, 95% CI 0.26-0.40; ungraded).
1 finding from 1 review