Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

38 questions · 39 findings · 3 reviews

No studies found 13 · 33.3%GRADE not reported 6 · 15.4%Very low 15 · 38.5%Low 4 · 10.3%Moderate 1 · 2.6%High 0 · 0%

Foam sclerotherapy vs placebo

Complications ‐ DVT · participants with varicose veinsa

It is very uncertain whether foam sclerotherapy changes complications ‐ DVT compared with placebo (very low certainty).

1 finding from 1 review

Foam sclerotherapy vs foam sclerotherapy

Cosmetic appearance · participants with varicose veinsa

It is very uncertain whether foam sclerotherapy changes cosmetic appearance (self‐described cosmetic improvement) compared with foam sclerotherapy (very low certainty).

1 finding from 1 review

Foam sclerotherapy vs foam sclerotherapy

Number of thromboembolic complications · participants with varicose veinsa

It is very uncertain whether foam sclerotherapy changes complications ‐ thromboembolic compared with foam sclerotherapy (very low certainty).

1 finding from 1 review

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Disease‐specific quality of life · people requiring intervention for short saphenous vein varices
2 findings from 1 review

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Recanalisation or persistence of reflux at 6 weeks · people requiring intervention for short saphenous vein varices

Ultrasound‐guided foam sclerotherapy showed no clear difference in recanalisation or persistence of reflux at 6 weeks compared with conventional surgery (low certainty).

1 finding from 1 review

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Recurrence of reflux at 1 year · people requiring intervention for short saphenous vein varices

Ultrasound‐guided foam sclerotherapy showed no clear difference in recurrence of reflux at 1 year compared with conventional surgery (low certainty).

1 finding from 1 review