Selective serotonin reuptake inhibitors vs placebo
- no estimate extracted1 study · 27 participantsVery low
It is very uncertain whether selective serotonin reuptake inhibitors (SSRI) changes study dropouts at 6‐12 weeks compared with tricyclic antidepressant (TCA) (very low certainty).
It is very uncertain whether selective serotonin reuptake inhibitors (SSRI) changes adverse effects during antidepressant treatment period (0‐12 weeks) compared with tricyclic antidepressant (TCA) (very low certainty).
It is very uncertain whether selective serotonin reuptake inhibitors (SSRI) changes improvement in depression at 6‐12 weeks: HAM‐D score (dichotomized) compared with tricyclic antidepressant (TCA) (very low certainty).
It is very uncertain whether selective serotonin reuptake inhibitors (SSRI) changes improvement in depression at 6‐12 weeks: CGI‐I (score of 1 or 2) compared with tricyclic antidepressant (TCA) (very low certainty).
It is very uncertain whether selective serotonin reuptake inhibitors (SSRIs) changes efficacy as a dichotomous outcome compared with tricyclic antidepressants (TCAs) (very low certainty).
It is very uncertain whether selective serotonin reuptake inhibitors (SSRIs) changes dropouts due to any cause (acceptability) compared with tricyclic antidepressants (TCAs) (very low certainty).
SSRI probably leads to higher participant perception of change with treatment compared with placebo (moderate certainty).
SSRI probably leads to higher participant satisfaction with intercourse compared with placebo (moderate certainty).
SSRI may leads to higher study withdrawal due to adverse events compared with placebo (low certainty).
SSRI probably leads to higher perceived control over ejaculation compared with placebo (moderate certainty).
SSRI probably leads to higher participant distress about PE compared with placebo (moderate certainty).
SSRI probably leads to higher adverse events compared with placebo (moderate certainty).