Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

15 questions · 16 findings · 2 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 18.8%Low 4 · 25%Moderate 9 · 56.3%High 0 · 0%

SPECIALISED TEAM vs usual care

Compliance with treatment ‐ treatment stopped in spite of need ‐ by one year · people with psychosis

SPECIALISED TEAM probably leads to lower compliance with treatment ‐ treatment stopped in spite of need ‐ by… compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

SPECIALISED TEAM vs usual care

Compliance with treatment ‐ treatment stopped in spite of need ‐ by two years · people with psychosis

SPECIALISED TEAM showed no clear difference in compliance with treatment ‐ treatment stopped in spite of need ‐ by… compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

SPECIALISED TEAM vs usual care

Service use: 2. Not hospitalised ‐ by five years · people with psychosis

SPECIALISED TEAM showed no clear difference in service use: 2. Not hospitalised ‐ by five years compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

SPECIALISED TEAM vs usual care

Social outcomes: 1. Not living independently ‐ by 5 years · people with psychosis

SPECIALISED TEAM probably leads to lower social outcomes: 1. Not living independently ‐ by 5 years compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

SPECIALISED TEAM vs usual care

Social outcomes: 2. Not working or in education ‐ by 5 years · people with psychosis

SPECIALISED TEAM showed no clear difference in social outcomes: 2. Not working or in education ‐ by 5 years compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

PHASE SPECIFIC TREATMENT (RISPERIDONE + CBT) + SPECIALISED TEAM vs SPECIALISED TEAM

Progression to psychosis ‐ by 12 months · people with psychosis

PHASE SPECIFIC TREATMENT (RISPERIDONE + CBT) + SPECIALISED TEAM probably leads to lower progression to psychosis ‐ by 6 months compared with SPECIALISED TEAM (moderate certainty).

2 findings from 1 review

Extended specialised early intervention (SEI) teams vs standard SEI teams plus treatment

Global state: recovery (assessed by symptom remission over a specified time period, as defined by study) · recent‐onset psychosis

It is very uncertain whether extended specialised early intervention (SEI) teams changes global state: recovery (assessed by symptom remission over a… compared with standard SEI teams plus treatment (very low certainty).

1 finding from 1 review

Extended specialised early intervention (SEI) teams vs standard SEI teams plus treatment

Service use: disengagement from services(assessment varied) · recent‐onset psychosis

Extended specialised early intervention (SEI) teams may leads to lower service use: disengagement from services(assessment varied) compared with standard SEI teams plus treatment (low certainty).

1 finding from 1 review

Extended specialised early intervention (SEI) teams vs standard SEI teams plus treatment

Service use: admission to psychiatric hospital (assessed by proportion admitted at end of treatment) · recent‐onset psychosis

Extended specialised early intervention (SEI) teams showed no clear difference in service use: admission to psychiatric hospital at end of treatment… compared with standard SEI teams plus treatment (low certainty).

1 finding from 1 review

Extended specialised early intervention (SEI) teams vs standard SEI teams plus treatment

Adverse effects/events: death ‐ all‐cause mortality(assessed by patient records) · recent‐onset psychosis

Extended specialised early intervention (SEI) teams showed no clear difference in adverse effects/events: death ‐ all‐cause mortality(assessed by… compared with standard SEI teams plus treatment (low certainty).

1 finding from 1 review